T lymphocytes Flashcards
how many stages are there in the response of T lymphocytes to infection?
5
what’s the first stage of T-lymphocytes response to infection by a pathogen?
pathogens invade body cells or are taken in by phagocytes.
what’s the second stage of T-lymphocytes response to infection by a pathogen?
the phagocyte places antigens from the pathogen on its CSM
what’s the third stage of T-lymphocytes response to infection by a pathogen?
receptors on a specific helper T cell fit exactly onto these antigens.
what’s the fourth stage of T-lymphocytes response to infection by a pathogen?
this attachment activates the T cell to divide rapidly by mitosis and form a clone of genetically identical cells.
What are the 4 things that the cloned T cells do to fight the pathogen after they have been created through mitotic division?
they develop into memory cells that enable a rapid response to future infections by the same pathogen.
stimulate phagocytes to engulf pathogens by phagocytosis.
stimulate B cells to divide and secrete their antibody.
activate cytotoxic T cells.
how do cytotoxic t cells kill infected cells?
they produce a protein named perforin which makes holes in the CSM. This makes the CSM freely permeable to all substances resulting in the cell dying.
where do t cells mature?
thymus gland
are t cells involved in cell-mediated immunity or humoral immunity?
cell-mediated immunity
what is an antigen?
a part of an organism that is recognised as non-self by the immune system and so stimulates an immune response.
where do b cells mature?
bone marrow
are be cells involved in humoral or cell-mediated immunity?
humoral
why is humoral immunity named humoral immunity?
humor is an old word for body fluids and humoral immunity involves antibodies which are found in body fluids.
how many steps are there regarding the role of b cells in immunity?
7
what’s the first step in the role of b cells in immunity?
the surface antigens of invading pathogens are taken up by a b cell