T lymphocytes Flashcards

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1
Q

how many stages are there in the response of T lymphocytes to infection?

A

5

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2
Q

what’s the first stage of T-lymphocytes response to infection by a pathogen?

A

pathogens invade body cells or are taken in by phagocytes.

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3
Q

what’s the second stage of T-lymphocytes response to infection by a pathogen?

A

the phagocyte places antigens from the pathogen on its CSM

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4
Q

what’s the third stage of T-lymphocytes response to infection by a pathogen?

A

receptors on a specific helper T cell fit exactly onto these antigens.

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5
Q

what’s the fourth stage of T-lymphocytes response to infection by a pathogen?

A

this attachment activates the T cell to divide rapidly by mitosis and form a clone of genetically identical cells.

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6
Q

What are the 4 things that the cloned T cells do to fight the pathogen after they have been created through mitotic division?

A

they develop into memory cells that enable a rapid response to future infections by the same pathogen.

stimulate phagocytes to engulf pathogens by phagocytosis.

stimulate B cells to divide and secrete their antibody.

activate cytotoxic T cells.

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7
Q

how do cytotoxic t cells kill infected cells?

A

they produce a protein named perforin which makes holes in the CSM. This makes the CSM freely permeable to all substances resulting in the cell dying.

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8
Q

where do t cells mature?

A

thymus gland

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9
Q

are t cells involved in cell-mediated immunity or humoral immunity?

A

cell-mediated immunity

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10
Q

what is an antigen?

A

a part of an organism that is recognised as non-self by the immune system and so stimulates an immune response.

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11
Q

where do b cells mature?

A

bone marrow

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12
Q

are be cells involved in humoral or cell-mediated immunity?

A

humoral

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13
Q

why is humoral immunity named humoral immunity?

A

humor is an old word for body fluids and humoral immunity involves antibodies which are found in body fluids.

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14
Q

how many steps are there regarding the role of b cells in immunity?

A

7

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15
Q

what’s the first step in the role of b cells in immunity?

A

the surface antigens of invading pathogens are taken up by a b cell

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16
Q

what’s the second step in the role of b cells in immunity?

A

the b cell processes the antigens and presents them on its surface

17
Q

what’s the third step in the role of b cells in immunity?

A

helper t cells attach to the processed antigens on the b cell therby activating the b cell

18
Q

what’s the fourth step in the role of b cells in immunity?

A

the b cell is now activated to divide by mitosis to give a clone of plasma cells

19
Q

what’s the fifth step in the role of b cells in immunity?

A

the cloned plasma cells produce and secrete the specific antibody that exactly fits the antigen on the pathogen’s surface

20
Q

what’s the sixth step in the role of b cells in immunity?

A

the antibody attaches to antigens on the pathogen and destroys them

21
Q

what’s the sixth step in the role of b cells in immunity?

A

some b cells develop into memory cells. these can respond to future infections by the same pathogen by dividing rapidly and developing into plasma cells that produce antibodies. this is the secondary response