T-HELPER CELLS Flashcards

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1
Q

T-Helper cells also known as

A

CD4+ T-Cells

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2
Q

Which factors determine the type of inmune response of a CD4+ T-Cell

A
  1. Type of antigen
  2. Cytokines encountered
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3
Q

Once a T-Helper Cell identifies an antigen it becomes

A

SPECIFIC Type of T-Helper Cell

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4
Q

Th-1 Cells function

A

Activation of Macrophages and Cytotoxic T-cells
(KILLS VIRUS and INTRACELLULAR BACTERIA)

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5
Q

Production of Th-1 Cells is induced by

A

IFN-Gamma (produced by NK Cells)
IL-12

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6
Q

Th-1 Cells produce _________ after activation

A

IFN-Gamma

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7
Q

Th-2 Cells function

A

Activation of Eosinophils and promotion of class switching to IgE
(PARASITE DEFENSE)

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8
Q

Production of Th-2 Cells is induced by

A

IL-2 and IL-4

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9
Q

Th-2 Cells produce ___________

A

IL-4
IL-5
IL-6
IL-10

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10
Q

Th-17 cells function

A

Activate NEUTROPHILS (phagocytes) to protect against EXTRACELLULAR MICROBES.

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11
Q

Production of Th-17 cells is induced by

A

TGF-Beta
IL-1
IL-6

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12
Q

Th-17 cells produce ____________

A

IL-17, IL-21, IL-22

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13
Q

Th-Reg cells function

A

PREVENTION of AUTOINMUNITY and DECREASE of INMUNE RESPONSE

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14
Q

Production of Th-Reg cells is induced by

A

TGF-Beta and IL-2

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15
Q

Th-Reg cells produce

A

TGF-B, IL-10, IL-35

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