T-HELPER CELLS Flashcards
T-Helper cells also known as
CD4+ T-Cells
Which factors determine the type of inmune response of a CD4+ T-Cell
- Type of antigen
- Cytokines encountered
Once a T-Helper Cell identifies an antigen it becomes
SPECIFIC Type of T-Helper Cell
Th-1 Cells function
Activation of Macrophages and Cytotoxic T-cells
(KILLS VIRUS and INTRACELLULAR BACTERIA)
Production of Th-1 Cells is induced by
IFN-Gamma (produced by NK Cells)
IL-12
Th-1 Cells produce _________ after activation
IFN-Gamma
Th-2 Cells function
Activation of Eosinophils and promotion of class switching to IgE
(PARASITE DEFENSE)
Production of Th-2 Cells is induced by
IL-2 and IL-4
Th-2 Cells produce ___________
IL-4
IL-5
IL-6
IL-10
Th-17 cells function
Activate NEUTROPHILS (phagocytes) to protect against EXTRACELLULAR MICROBES.
Production of Th-17 cells is induced by
TGF-Beta
IL-1
IL-6
Th-17 cells produce ____________
IL-17, IL-21, IL-22
Th-Reg cells function
PREVENTION of AUTOINMUNITY and DECREASE of INMUNE RESPONSE
Production of Th-Reg cells is induced by
TGF-Beta and IL-2
Th-Reg cells produce
TGF-B, IL-10, IL-35