T cell immunity

Question 1

What does IL-1 do?

Answer 1

fever, T cell activation, macrophage activation

Question 2

What does IL-2 do?

Answer 2

IL-2 is a T-cell growth factor so it does T-cell proliferation

Question 3

what kind(s) of pathogen do Th1 cells fight

Answer 3

intracellular bacteria

Question 4

what kind(s) of pathogen do Th2 cells fight

Answer 4

parasites

Question 5

what kind(s) of pathogen do Th17 cells fight

Answer 5

extracellular bacteria and fungi

Question 6

What do Th1 cells secrete?

Answer 6

IFN-gamma (activates macrophages and promotes IgG antibody production),

Question 7

what is type IV hypersensitivity and which helper T cell is it associated with?

Answer 7

delayed onset hypersensitivity in which a cell-mediated immune response causes neutrophils to accumulate and inflame the site of infection; it is associated with Th1 cells

Question 8

what immune effector cells are mobilized by a Th2-mediated response?

Answer 8

mast cells, basophils, eosinophils

Question 9

IL-6 and TGF-beta cause undifferentiated CD4+ cells to become which type of helper cell?

Answer 9

Th17

Question 10

What cytokine do Th2 cells secrete?

Answer 10

IL-4, IL-5, and IL-13