Epithelia Flashcards

0
Q

What molecules comprise adhering junctions (aka zonula adherens)?

A

Cadherins, which connect actin cytoskeleton from one cell to actin cytoskeleton of another cell

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1
Q

What molecules comprise tight junctions?

A

Claudins and occludins

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2
Q

What comprises desmosomes?

A

Cadherins, which bind intermediate filaments of one cell to intermediate filaments of another cell

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3
Q

What protein comprises gap junctions?

A

Connexin, a transmembrane protein, which forms connexons, which form desmosomes

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4
Q

What does the junctional complex consist of?

A

Zonula occludens (tight junction), zonula adherens (adhering junction) and macula adherens (desmosome)

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5
Q

What special purpose do hemidesmosomes serve?

A

Anchor the cell to the BM, via transmembrane proteins known as integrins, which bind to extracellular laminins in the basement membrane

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