Innate Immunity Flashcards
1
Q
what PAMPs do TLR1:TLR2
A
bacterial triacylated lipopeptides
2
Q
what PAMPs does TLR2 recognize
A
bacterial peptidoglycan, LTA
3
Q
what does TLR4 recognize
A
gram negative bacterial LPS, fungal mannans, viral envelop proteins, host heat shock proteins
4
Q
what does TLR5 recognize
A
bacterial flagellin
5
Q
what does TLR2:TLR6 recognize
A
bacterial LTA
6
Q
which TLR recognizes viral double-stranded RNA
A
TLR3
7
Q
which TLRs recognize viral single stranded RNA
A
TLR7 and TLR8
8
Q
what does TLR9 recognize
A
viral and bacterial unmethylated CpG DNA
9
Q
which TLRs are found on the cell membrane
A
TLR1:TLR2, TLR2, TLR4, TLR5, TLR2:TLR6
10
Q
which TLRs are found in the endosomal membrane
A
TLR3, TLR7, TLR8, TLR9