Sz- Neurotransmitters as an explanation Flashcards
What is a neurotransmitter?
Brain chemicals released from synaptic vesicles. Neurotransmitters relay signals from on neuro to another across a synapse. Neurotransmitters
What are the names of some 1st generational drugs used for treatments of Sz?
chlorpromazine and reserpine
What are the side effect of chlorpromazine and reserpine?
Parkinsons - tremors and muscle rigity
When in excess of dopamine, which pathway is the cause of positive symptoms?
Mesolimbic pathway
When there is a lack of dopamine, which pathway is the cause of negative symptoms?
Mesocortical pathway
Name a second generation drug?
Clopazine
Is dopamine dysregulation in the stratum a common pathway to psychosis.
yes
Mate I dont know what this means
What is Catherine Tenn study related to Sz?
She found that the rats given 9 amphetimines injections over 3 weeks showed various Sz like symptoms.
The dopamine antagonist were successful in reversing this these effect.
Which groups in society are more likely to be diagnosed with Sz?
Second generation immigrants
What did Wim Veling discover? And what does it infer?
Showed Morroco immigrants were more likely to get Sz than Turkish immigrants.
Suggests that environmental factors such as social stress may interact with neurochemistry making some people more prone to psychosis
What applications are there for using neurotransmitters as an explanation for Sz?
Drug therapy