Syphilis Flashcards

1
Q

What is Syphilis?

A

A sexually transmitted disease

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2
Q

What agent causes Syphilis?

A

Treponema palladium (gram - spirochete)

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3
Q

What is a common nickname used for Syphilis?

A

“The great imitator”

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4
Q

What are the three stages of Syphilis?

A
  1. Primary
  2. Secondary
  3. Late/latent
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5
Q

How is Syphilis transmitted?

A
  1. Direct contact with a lesion

2. Pregnant woman to child

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6
Q

Where are the lesions most commonly located?

A

Vagina, penis, anus, rectum, mouth

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7
Q

Can you contract Syphilis by touching an inanimate object?

A

No

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8
Q

What symptoms occur in the primary stage of Syphilis?

A

A chancre - firm, round, painless lesion (single or multiple)

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9
Q

What is the incubation period for primary Syphilis?

A

10 - 90 days (21 median)

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10
Q

Since the chancre will typically heal without treatment within 3 to 6 weeks, does an infected individual still need to be treated for Syphilis?

A

YES, infection progresses if not treated

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11
Q

What is the classic symptom of Syphilis during the second stage?

A

Non-pruritic body rash (palms of hands and soles of feet)

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12
Q

What are some associated symptoms that accompany the rash during the second stage of Syphilis?

A

Fever, sore throat, patchy hair loss, headaches, weight loss, muscle aches, fatigue, lymphadenopathy

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13
Q

What % of people with Syphilis will progress to the late/latent stage?

A

15%

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14
Q

When will the late/latent stage occur?

A

10 to 20 years after initial infection

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15
Q

What complications occur with the late/latent stage?

A
  1. Internal organ damage to the brain, CNS, eyes, heart and vascular system, liver, bones, joints
  2. Dementia, paralysis, gradual blindness, coordination difficulty – can cause death
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16
Q

If you don’t have a visible sore, can you be infectious?

A

Yes

17
Q

How do you screen for Syphilis?

A

Venereal Disease Research Lab (VDRL) or rapid plasma reagent (RPR) tests

18
Q

How do you diagnose Syphilis?

A

Fluorescent treponemal antibody absorption test (FTA-ABS) and Treponema pallidum particle agglutination assay (TPPA) - confirmatory test

19
Q

If diagnosed with Syphilis, you are 2-5 times more likely to become infected with?

A

HIV - chancre increases exposure/incidence rate

20
Q

What is the treatment for Syphilis?

A

Parenteral penicillin (dose & type depends on stage)

21
Q

Do you develop immunity after being infected with Syphilis?

A

No, re-infection can occur