Synapses And Role Of Neurotransmitters

Question 0

Where is the electrical synapse more common

Answer 0

In glial cells over Neurones

Question 1

What allows the wave of contraction in the heart to occur?

Answer 1

An electric synapse allowing bi directional ionic current allows synchronous activity ie. if one cell excited, 2nd cell gets excited

Question 2

Describe sequence of events in a chemical synapse

Answer 2

Depolarize terminal bouton 
Triggers Ca2+ channel opening so influx 
Neurotransmitter released by exocytosis 
Diffusion across synapse 
Bind to receptors on post synaptic membrane causing depolarization

Question 3

How can one neurotransmitter cause so many different responses in different parts of the body

Answer 3

One neurotransmitter can bind to several receptor sub types

Question 4

What are the diff type of receptor signaling mechanisms

Answer 4

Ionotropic - ligand gated channel.

Metabotropic - activates G Pn + cascade

Question 5

What are the electrical effects on ionotropic receptors and we what molecule influences it?

Answer 5

Excitatory post synaptic potential : Na+
Inhibitory post synaptic potential: Cl-

NB: small = one vesicle released into synapse

Question 6

Define spatial summation

Answer 6

Summing of post synaptic potential generated at separate synapses

Question 7

Define temporal summation

Answer 7

Summing of post synaptic potentials generated at same synapse if they occur in rapid succession