Synapse Flashcards

1
Q

structure electrical synapse

A

gap junction

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2
Q

gap junction, what is permeability regulated by?

A

cytosolic concentration of free ca2+ or cytosolic ph

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3
Q

gap junction, what kind of complex does it have?

A

hexameric

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4
Q

6 connexins form a

A

connexon

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5
Q

electrical synapse also permit

A

synchronization of activity

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6
Q

synchronization, in neurons that have a

A

similar function

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7
Q

gap junctions, permits movement of ?

A

atp and second messengers

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8
Q

chemical neurotransmitters are? and eg?

A

small molecules in small clear vesicles

ach, gaba, glutamate, glycine

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9
Q

chemical neurotransmitters, large molecules in dense core vesicles

A

neuropeptides

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10
Q

release of chemical neurotransmitters is

A

ca dependent

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11
Q

neural basis of learning and memory, 2 changes

A

functioning of neurons in brain could change

structure of neurons could change

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12
Q

electrical properties

A

instantaneous
no loss of signal
similar time course

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13
Q

chemical properties

A

delayed
signal greatly reduced
longer response

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14
Q

advantage of electrical signal

A

no synaptic delay
allows synchronization of many cells quickly
can transmit metabolic signals between cells

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15
Q

disadvantage of electrical signal

A

cannot convert signal from pre to post, from excitatory to inhibitory

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16
Q

chemical synapse, glytamate

A

opens na+ channels,

excitatory

17
Q

chemical synapse, GABA

A

opens cl- channels

inhibitory

18
Q

spatial summation

A

eg if 3 neurons fire the individual signal is all below threshold,
when the signals build up together they are able to go and create suprathreshold signal
action potential

19
Q

temporal summation

A

if 2 subthreshold potentials arrive at the trigger zone within a short period of time they may sum and initiate a action potential