Signalling To Cells Flashcards
Integrins are primarily found
2 answers
in cell matrix junctions
These also function in cell signalling
Cadherins are
Cell - cell junctions such as adherens junctions and desmosomes
Ca2+ dependent
Selectins
Temporary cell-cell adhesion
There are 3 types of strong cell junctions
Communication junctions
Occlusion junctions
Anchoring junctions
Gap junctions what do they do
Allows direct and rapid cell-cell communication through cytoplasmic bridges
Gap junctions can —— or close to regulate —– ——— or — through it
Open
Small molecules
Ions
Tight junctions are
Occludin junctions
Tight junctions do what In cells
2 proteins
They fuse adjacent cells together using proteins
Claudin and occludin
Making a dynamic barrier
Tight junctions form the
And what do they prevent
Blood brain barrier
Preventing harmful substances from entering the extra cellular fluid of the brain
Anchoring junctions can attach to both
the cell - cell or the extra cellular matrix
Anchoring junctions have CAMs in cell-cell junctions called
What does it do
Cadherins which connect with one another in the intercellular space
Anchoring junctions in cell-matrix junctions use CAMs called
Integrins
Membrane protein that can bind to signal molecules
Anchoring junctions combine to mechanically
Strengthen the tissues
The protein linkages are very strong it allows sheets of tissues in anchoring junctions to resist
To resist Damage from stretching
Anchoring junctions have spaces in between it allowing…
This movement is known as ..
Materials to pass through
Paracellular pathway
