endocrine 3 Flashcards

1
Q

3 main families of hormones

A

amine derived
peptide derived
lipid/phospholipid hormones

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2
Q

amine derived from

A

tyrosine
histadine
tryptophan eg throxine

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3
Q

peptide hormones

water soluble

A

small peptide hormones (TRH)
protein hormones (insulin)
glycoprotein (LH)

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4
Q

lipid and phospholipid

water insoluble

A

prostoglandins

steroid hormones, cholesterol, testosterone

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5
Q

Kd = (hormone receptor interactions)

A

Kd= [H][L]/[HL]

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6
Q

limiting step is

A

hormone binding

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7
Q

secondary messengers

A

cAMP
cGMP
Ca2+ and calmodulin

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8
Q

conc of hormones is determined by 3 factors

A

rate of release
rate of delivery
rate of degradation and elimination

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9
Q

hydrophilic hormones

5 answers

A
cell surface transmembrane receptors
channel linked receptors
enzyme receptors (secondary messenger)
tyrosine kinase (secondary messenger)
G protein linked receptors (secondary messenger)
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10
Q

hydrophobic hormones

A

cytoplasmic receptors

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11
Q

problems with hormonal feedback loop

3 answers

A

active tumors of glands
loss of glands- autoimmune disease
loss response to hormone

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12
Q

hypothalamic hormones to pituitary are what type of hormones

A

trophic hormones

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13
Q

hormones run down the ———————- axon to the postierior piutuitary

A

paraventricular

supaventricular

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14
Q

all the anterior pituitary glands hormones are ______ except __________

A

peptides

dopamine because its alanine

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15
Q

all anterior pituitary glands hormones bind to _______ except ______

A

G coupling

dopamine

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16
Q

ADH, Vagus— what does it reduce and trigger

A

reduces plasma volume

triggers baroreceptorsin aortic arch and carotid sinus which sends signals via nerves to CNS

17
Q

ADH causes

5 answers

A
collecting duct to insert aquaporin 2
stimulates NaCl uptake in assending loop of henle
increase vasoconstriction
increase water retention 
increase blood pressure
18
Q

oxytocin causes

A

contraction of myoepithelial cells in mammary gland for milk release
contraction of uterus during birth

19
Q

GH causes increased

A

protein production
cell division
cell size
after growth plates close, proportionate growth stops

20
Q

Gh induces what

6 answers

A
expression of somatomedins
increase cartilage and bone growth
increase lipid metabolism
decrease carbohydrate metabolism
increase AA uptake
increase RNA transcription/translation
21
Q

what regulated blood Ca2+ levels

A

parathyroid hormone