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Pharmacology Unit 2 > Sympathetic Drug Classifications > Flashcards

Sympathetic Drug Classifications Flashcards

1
Q

drug classifications of sympathetic nervous system

A 
adrenergic agonists 
alpha 1 adrenergic agonists 
alpha 1 adrenergic blockers
beta 1 adrenergic agonists
beta 2 adrenergic agonists
selective beta 1 blockers
non-selective beta blockers
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2
Q

MOA of alpha 1 adrenergic agonists

A

alpha 1 receptor stimulated
contraction of smooth muscle, vasoconstriction, increased BP, vasoconstriction of nasal passages causing decongestant effect

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3
Q

uses for alpha 1 adrenergic agonists

A

increase circulation of vital organs
increase BP
promote decongestion

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4
Q

alpha 1 adrenergic agonist drug examples

A

ephedrine

phenylephrine (Neo-synephrine ®)

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5
Q

side effects of alpha 1 adrenergic agonists

A

slows digestion and urination

excessive nasal dryness

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6
Q

MOA of adrenergic agonists

A

stimulates all alpha and beta receptors

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7
Q

MOA of adrenergic agonists

A

stimulates all alpha and beta receptors

vasoconstriction and increased BP

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8
Q

adrenergic agonist drugs

A

epinephrine (Adrenaline ®)

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9
Q

uses for adrenergic agonists

A

allergic reactions/anaphylaxis, shock, cardiac arrhythmias

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10
Q

side effects of adrenergic agonists

A

increased HR and BP

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11
Q

MOA of alpha 1 adrenergic blockers

A

binds to alpha 1 receptors and blocks them

relaxes smooth muscle, vasodilation, decreased blood pressure, increased uterine flow

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12
Q

alpa 1 adrenergic blocker drugs

A

prazosin (MInipress®)
terazosin (Hytrin®)
doxazosin (Cardura®)

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13
Q

uses for alpha 1 adrenergic blockers

A

hypertension, benign prostatic hyperplasia

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14
Q

side effects and patient teaching of alpha 1 adrenergic blockers

A

orthostatic hypotension- caution with position changes

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15
Q

MOA of beta 1 adrenergic agonists in low dose

A

stimulates dopamine receptors in kidneys causing vasodilation and increased renal blood flow

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16
Q

MOA of beta 1 adrenergic agonists in moderate dose

A

stimulates beta 1 receptors causing increased force of contraction and cardiac output

17
Q

MOA of beta 1 adrenergic agonists in high dose

A

stimulates alpha 1 receptors causing vasoconstriction and increase in BP

18
Q

beta 1 adrenergic agonist drugs

A

dobutamine (Dobutamine®)

19
Q

uses for beta 1 adrenergic agonist drugs

A

treatment of shock, high BP, to increase heart function

20
Q

side effects of beta 2 adrenergic agonist drugs

A

overstimulation of heart, CNS irritation

21
Q

MOA of beta adrenergic agonist drugs

A

stimulate beta 2 receptors

relaxation of smooth muscle of lungs causing bronchodilation, relaxation of smooth muscle of uterus

22
Q

beta 2 adrenergic agonist drugs

A

albuterol (Proventil®, Ventolin®)
terbutaline (Brethine®)
formoterol (Foradil®)
salmeterol (Serevent®)

23
Q

uses for beta 2 adrenergic agonists

A

Asthma, respiratory illness, preterm labor

24
Q

Side effects of beta 2 adrenergic agonists

A

Tachycardia, jittery, tremors, headache

25
Q

MOA selective beta one blockers

A

beta 1 receptor is blocked which antagonizes beta 1 effects of NE and EPI
Decreased force of contraction, cardiac output, HR, conduction, and BP

26
Q

Uses for selective beta 1 blockers

A

Hypertension, angina, arrhythmias, tachycardia, migraines, glaucoma, heart failure

27
Q

Selective beta 1 blocker drugs

A

atenolol (Tenormin®)

metoprolol (Lopressor®)

28
Q

Side effects and patient teaching of beta 1 blocker drugs

A

Drowsiness, G.I. upset, CNS depression, bradycardia, mental depression
Monitor serum lipid levels in glucose levels in diabetics

29
Q

MOA of non-selective beta blockers

A

Block beta 1 and beta 2 receptors

Decrease force of contraction, cardiac output, HR, conduction, and BP

30
Q

uses for non-selective beta blockers

A

Hypertension, arrhythmias, angina, tachycardia, migraines, glaucoma, heart failure

31
Q

non-selective beta blocker drugs

A

nadolol (Corgard®)
propanolol (Inderal®)
timolol (Blocadren®)

32
Q

contraindication of non selective beta blockers

A

in asthma and respiratory disease patients can trigger respiratory distress

33
Q

side effects and patient teaching of nonselective beta blockers

A

Drowsiness, G.I. upset, CNS depression, bradycardia, mental depression
Are serum lipid levels and glucose levels in diabetics

34
Q

What do all beta blockers and in

A

“olol”

35
Q

what do all alpha 1 adrenergic blocker drugs end in

A

“azosin”

Pharmacology Unit 2 (8 decks)

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