Sympathetic Drug Classifications Flashcards
drug classifications of sympathetic nervous system
adrenergic agonists alpha 1 adrenergic agonists alpha 1 adrenergic blockers beta 1 adrenergic agonists beta 2 adrenergic agonists selective beta 1 blockers non-selective beta blockers
MOA of alpha 1 adrenergic agonists
alpha 1 receptor stimulated
contraction of smooth muscle, vasoconstriction, increased BP, vasoconstriction of nasal passages causing decongestant effect
uses for alpha 1 adrenergic agonists
increase circulation of vital organs
increase BP
promote decongestion
alpha 1 adrenergic agonist drug examples
ephedrine
phenylephrine (Neo-synephrine ®)
side effects of alpha 1 adrenergic agonists
slows digestion and urination
excessive nasal dryness
MOA of adrenergic agonists
stimulates all alpha and beta receptors
MOA of adrenergic agonists
stimulates all alpha and beta receptors
vasoconstriction and increased BP
adrenergic agonist drugs
epinephrine (Adrenaline ®)
uses for adrenergic agonists
allergic reactions/anaphylaxis, shock, cardiac arrhythmias
side effects of adrenergic agonists
increased HR and BP
MOA of alpha 1 adrenergic blockers
binds to alpha 1 receptors and blocks them
relaxes smooth muscle, vasodilation, decreased blood pressure, increased uterine flow
alpa 1 adrenergic blocker drugs
prazosin (MInipress®)
terazosin (Hytrin®)
doxazosin (Cardura®)
uses for alpha 1 adrenergic blockers
hypertension, benign prostatic hyperplasia
side effects and patient teaching of alpha 1 adrenergic blockers
orthostatic hypotension- caution with position changes
MOA of beta 1 adrenergic agonists in low dose
stimulates dopamine receptors in kidneys causing vasodilation and increased renal blood flow
MOA of beta 1 adrenergic agonists in moderate dose
stimulates beta 1 receptors causing increased force of contraction and cardiac output
MOA of beta 1 adrenergic agonists in high dose
stimulates alpha 1 receptors causing vasoconstriction and increase in BP
beta 1 adrenergic agonist drugs
dobutamine (Dobutamine®)
uses for beta 1 adrenergic agonist drugs
treatment of shock, high BP, to increase heart function
side effects of beta 2 adrenergic agonist drugs
overstimulation of heart, CNS irritation
MOA of beta adrenergic agonist drugs
stimulate beta 2 receptors
relaxation of smooth muscle of lungs causing bronchodilation, relaxation of smooth muscle of uterus
beta 2 adrenergic agonist drugs
albuterol (Proventil®, Ventolin®)
terbutaline (Brethine®)
formoterol (Foradil®)
salmeterol (Serevent®)
uses for beta 2 adrenergic agonists
Asthma, respiratory illness, preterm labor
Side effects of beta 2 adrenergic agonists
Tachycardia, jittery, tremors, headache