Parasympathetic Drug Classifications

Question 1

types of cholinergics/parasympathomimetics

Answer 1

direct acting cholinergic agonists

indirect acting cholinergic agonists

Question 2

MOA of direct acting cholinergic agonists

Answer 2

stimulate/bind to mucarinic receptors in parasympathetic division
mimics ACH

Question 3

drug examples of direct acting cholinergic agonists

Answer 3

• acetylcholine
• pilocarpine (Pilocar®)
• bethanechol (Urecholine®)

Question 4

MOA of indirect acting cholinergic agonists

Answer 4

inhibit acetylcholinesterase (the enzyme that destroys ACH in synapse)
increases ACH

Question 5

drug examples of indirect acting cholinergic agonists

Answer 5

neostigmine (Prostigmin®)

Question 6

uses for indirect acting cholinergic agonists

Answer 6

urinary retention and intestinal stasis

Question 7

what is the antidote of anticholinergics

Answer 7

physostigmine (Eserine®)

Question 8

MOA of anticholinergics/parasympatholytics

Answer 8

bind to cholinergic receptor

act as blocker, competitive antagonism

Question 9

drug examples of anticholinergics/parasympatholytics

Answer 9

atropine
dicyclomine (Bentyl®)
ipratopium bromide (Atrovent®)

Question 10

side effects of anticholinergics/parasympatholytics

Answer 10

dry mouth, visual disturbances, urinary retention, constipation, tachycardia