ANS 2 Flashcards
other name for parasympathetic NS
cholinergic
rest and digest
functions of parasympathetic NS
- restoration of energy
- balance
parasympathetic NS stimulates how much of body
one part or one system
neurotransmitter of parasympathetic NS
acetylcholine (ACH)
where is ACH in parasympathetic NS
at ganglia and postganlgionic nerve endings
parasympathetic effect on heart
decreased HR, AV conduction, and contractility
parasympathetic effect on intestines
increased GI motility and secretions
parasympathetic effect on pupils
constriction (miosis)
parasympathetic effect on respiratory passages
bronchoconstriction
parasympathetic effect on urinary bladder
contraction
parasympathetic effect on urinary sphincter
relaxation
3 types of cholinergic receptors
- muscarinic
- nicotinic 1 (Nn)
- nicotinic 2 (Nm)
what are all cholinergic receptors stimulated by
ACH
where are muscarinic receptors located
cardiac and smooth muscle and glands
at parasympathetic postganglionic nerve endings
where are nicotinic 1 receptors located
at ganglia of parasympathetic nerves and sympathetic nerves (synapse area)
where are nicotinic 2 receptors located
somatic, neuromuscular junction of skeletal muscle
what do muscarinic receptors cause
- decreased HR
- bronchoconstriction
- increased digestion and GI secretions
- increased urination
- pupillary constriction
what happens when nicotinic 2 receptors are stimulated
muscle contracts
what are parasympathetic nerves
long preganglionic nerves
what are the 2 types of parasympathetic drug effects
parasympathomimetics and parasympatholytics
parasympathomimetics
drugs that mimic parasympathetic system
agonists and cholinergic
parasympatholytics
drugs that work against parasympathetic system
antagonists and anticholinergics
drug categories and subcategories of parasympathetic system
- cholinergics/parasympathomimetics:
- direct-acting cholinergic agonists
- indirect-acting cholinergic agonists - anticholinergics/parasympatholytics
cholinergic side effects
SLUDGE
salivation/sweating, lacrimation, diarrhea, GI upset, emesis