Surrénales : glucocorticoïdes Flashcards

1
Q

principaux signes et sx d’hypocorticisme

A

insuf surrénalienne

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2
Q

principaux signes et sx d’hypercorticisme

A

syndrome de cushing

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3
Q

nommer les stress qui augmentent le cortisol

A

maladie,hypoglycémie, jeune, hypovolémie, trauma

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4
Q

effets généraux du cortisol

A
  1. suppression générale des autres hormones
  2. anti-infl. et immunosuppresseurs
  3. HTA
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5
Q

cortisol sur les glucides

A

augmente la glycémie !!

aug. résistance à l’insuline , néoglucogenèse, synth. du glycogène

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6
Q

cortisol sur les lipides

A

aug lipolyse, etc–> gain pondéral

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7
Q

cortisol sur le coeur

A

HVG à long terme pcq augmente tout pour aug HTA

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8
Q

cortisol sur les reins

A

via MR –> rétention hydrosodée

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9
Q

effets cataboliques et conséquences du cortisol sur la peau

A

dim l’activité des fibroblastes et dim collagène et tissu conjonctif

–> peau mince, ecchymoses, dim cicatrisation, vergetures pourpres

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10
Q

effets osseux du cortisol

A

ostéoporose , rabsorption osseuse

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11
Q

effets du cortisol sur la formule sanguine

A
  1. aug hématopoïèse
  2. aug leucocytes (démargination)
  3. dim monocytes, lymphocytes, éosinophiles
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12
Q

effets anti-infl. du cortisol

A
  1. dim. cytokines

2. dim les médiateurs pro-infl.

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13
Q

effets du cortisol sur l’immunité

A

immunosuppresseur

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14
Q

cortisol diminue quels axes?

A

somatotrope, gonadotrope , thyréotrope

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