Surgical Management of Lung Cancer Flashcards

1
Q

What is the assessment of the patient used to determine?

A

Staging of the lung cancer

Fitness of the patient

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2
Q

What needs to be determined to stage lung cancer?

A

T, N and M status

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3
Q

What are common clinical findings in the history for lung cancer?

A

Pain (especially bone pain)

Headaches or neurological symptoms including personality change

Haematuria (presence of red blood cells in the urine)

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4
Q

What is haematouria?

A

Presence of red blood cells in the urine

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5
Q

What is presence of red blood cells in the urine called?

A

Haematuria

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6
Q

What are common clinical findings in the examination with lung cancer?

A

Recurrent laryngeal nerve palsy

Brachial plexus palsy

Superior vena cava obstruction (SVCO)

Supraclavicular lymph nodes

Soft tissue nodules

Chest wall masses

Pleural/pericardial effusion

Hepatomegaly (enlarged liver)

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7
Q

What is hepatomegaly?

A

Abnormally enlarged liver

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8
Q

What is abnormally enlarged liver called?

A

Hepatomegaly

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9
Q

What can chest X-rays be used to determine?

A

Pleural effusion

Chest wall invasion

Phrenic nerve palsy

Collapsed lobe or lung

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10
Q

What is pleural effusion?

A

Build of of excessive fluid between the pleura

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11
Q

What is the build up of excessive fluid between the pleura called?

A

Pleural effusion

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12
Q

What are some tests that are useful for staging cancer other than CT?

A

MRI

Bone scan

ECHO (echocardiogram)

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13
Q

What does ECHO stand for?

A

Echocardiogram

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14
Q

What is an echocardiogram (ECHO)?

A

Ultrasound scan used to look at the heart and nearby blood vessels

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15
Q

What is MRI useful for?

A

Determine degree of vascular and neurological involvement

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16
Q

What test is best for determining the degree of vascular and neurological involvement?

A

MRI

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17
Q

What is bone scan useful for?

A

Test for chest wall invasion and for bony metastasis

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18
Q

What test is best for checking chest wall invasion or bony metastasis?

A

Bone scan

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19
Q

What is an echocardiogram (ECHO) useful for?

A

Demonstrate presence or absence of significant pericardial effusion

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20
Q

What test is best for demonstrating the presence or absence of pericardial effusion?

A

Echocardiogram (ECHO)

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21
Q

What is used for the surgical staging of lung cancer?

A

Bronchoscopy

Mediastinoscopy

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22
Q

What is the fitness for surgery determined by?

A

Clinical assessment

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23
Q

What systems are looked at during the clinical assessment to determine if someone is fit for surgery?

A

Cardiovascular

Respiratory

Psychological

Other

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24
Q

What, in terms of the cardiovascular system, is check when determining fitness for surgery?

A

Angina

Heart problems

High blood pressure

Diabetes mellitus

Peripheral vascular disease

Smoking

Stroke

Carotid bruits

Heart murmors

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25
What is angina?
Chest pain due to not enough blood flow to the heart
26
What is chest pain due to not enough blood flow to the heart called?
Angina
27
What is carotid bruits?
Vascular murmur sound (bruit) heard over the carotid artery
28
What is a vascular murmur sound heard over the carotid artery called?
Carotid bruits
29
What is a heart murmur?
Unusual sound heard between heart beats
30
What is an unusual sound heard between heart beats called?
Heart murmur
31
What, in terms of the respiratory system, is check when determining fitness for surgery?
Barrel-chested COPD Smoking Asthmatic On oxygen Exercise capacity Previous thoractomy
32
What is barrel-chested?
Broad deep chest
33
What is a broad deep chest called?
Barrel-chested
34
What psychologically is checked when determining fitness for surgery?
Past history of mental illness Severe anxiety Social background Chronic pain problems
35
What additional things will be checked when determining fitness for surgery?
Pulmonary hypertension Permanent tracheostomy Rheutamoid artheritis Immobile patient Cirrhosis
36
What is cirrhosis?
Condition where the liver does not function properly due to long term damage
37
What is a condition where the liver does not function properly due to long term damage?
Cirrhosis
38
What is respiratory function testing determined by?
Spirometry Diffusion studies Arterial blood gasses on air V/Q scan
39
What is cardiac assessment determined by?
Electrocardiogram (ECG) Echocardiogram (ECHO) CT scan Exercise tolerance test (ETT) Coronary angiogram
40
What does ETT stand up for?
Exercise tolerance test
41
In terms of operating, what should you do if you are in doubt?
Do not operate
42
What is the goal for the surgical treatment of lung cancer?
Curative resection
43
What firm diagnosis is highly desirably before lung resection?
Malignancy
44
What are the aims of surgical treatment of lung cancer?
Curative resection Remove minimal amount of lung tissue Resection of parietal structure is feasible
45
What does peri-operative deaths mean?
During operation
46
What are some reasons for peri-operative deaths?
Acute respiratory distress syndrome (ARDS) Bronchopneumonia Myocardial infarction Pulmonary thromboendarectomy (PTE) Pneumothorax Intrathoracic bleeding
47
What does ARDS stand for?
Acute respiratory distress syndrome
48
What is acute respiratory distress syndrome (ARDS)?
The lungs cannot provide the bodies vital organs with enough oxygen
49
What is myocardial infarction?
Heart attack
50
What is the medical name for a heart attack?
Myocardial infarction
51
What does PTE stand for?
Pulmonary thromboendarectomy
52
What is a pulmonary thromboendarectomy (PTE)?
Operation that removes thrombus from pulmonary arteries
53
What is the operation that removes thrombus from the pulmonary arteries called?
Pulmonary thromboendarectomy (PTE)
54
What are some non-fatal surgical complications?
Post thoracotomy wound pain Empyema Wound infection Atrial fibrillation Myocardial infarction Post-op respiratory insufficiency Gastroparesis/constipation
55
What is atrial fibrillation?
Irregular and often abnormally fast heart rate
56
What is an irregular and often abnormally fast heart rate called?
Atrial fibrillation
57
What are some common problems with the staging of lung cancer?
Collapse of a lobe or lung makes tumour size difficult to asses Presence of another (usually small) pulmonary nodule Retrosternal thyroid Adrenal nodule CT head is not routinely performed preop
58
What is the operative mortality of the most dangerous procedure?
5-10%
59
What is the operative mortality of a pneumonectomy?
5-10%
60
What is the operative mortality of a lobectomy?
3-5%
61
What is the operative mortality of a wedge resection?
2-3%
62
What is the operative mortality of a open/close thoracotomy?
5%
63
What is the chance of a second primary within 5 years of the operation?
5%
64
What is the 5 year survival, post-operatively, of T1/2/3 and N\<2?
Between 40-70%
65
What is the 5 year survical, post operatively, of any N2?
16%