Drugs

Question 1

What is salbutamol?

Answer 1

B₂ receptor agonist

Question 2

What is terbutaline?

Answer 2

B₂ receptor agonist

Question 3

What is salmeterol?

Answer 3

Long acting B₂ receptor agonist

Question 4

What is formoterol?

Answer 4

Long acting B₂ receptor agonist

Question 5

What is ipratropium?

Answer 5

Antimuscurinic

Question 6

What is tiotropium?

Answer 6

Antimuscurinic

Question 7

What is theophylline?

Answer 7

Xanthine

Question 8

What is aminiophylline?

Answer 8

Xanthine

Question 9

What do B₂ receptor antagonists do?

Answer 9

Block sympathetic nervous system action on B₂ receptors, cauing bronchial dilation

Question 10

What do antimuscurinics do?

Answer 10

Block parasympathetic nervous system actions on muscurinic receptors, stopping bronchial constriction

Question 11

What are indications of B₂ receptor agonists?

Answer 11

Asthma

COPD

Question 12

What are indications for anti-muscurinics?

Answer 12

Chronic asthma (stage 4)

COPD (symptomatic relief)

SHOULD NOT BE USED ALONE

Question 13

What do xanthines do?

Answer 13

Cause bronchodilation

Question 14

How is theophylline administered?

Answer 14

Oral

Question 15

How is aminophylline administered?

Answer 15

Slow IV infusion

Question 16

What are indications for xanthines?

Answer 16

Asthma (3rd line drug)

COPD

Question 17

What is beclometasone?

Answer 17

Corticosteroid

Question 18

What is budesonide?

Answer 18

Corticosteroid

Question 19

What is prednisolone?

Answer 19

Corticosteroid

Question 20

How is beclometasone administered?

Answer 20

Inhaled

Question 21

How is budesonide administered?

Answer 21

Inhaled

Question 22

How is prednisolone administered?

Answer 22

Oral

Question 23

What do corticosteroids do?

Answer 23

Reduce inflammatory response in airways

Reduce oedema and mucus production in airways

Inhibit allergic reactions

Question 24

What are indications for inhaled corticosteroids?

Answer 24

Stage 2 asthma

COPD (in combination with Leukotreine antagonist)

Hayfever

Question 25

What are indications for oral corticosteroids?

Answer 25

Acute exacerbations of asthma/COPD

Question 26

What is motelukast?

Answer 26

Leukatriene receptor antagonist

Question 27

What is zafirlukast?

Answer 27

Leukotreine receptor antagonist

Question 28

What do leukotreine receptor antagonists do?

Answer 28

Block effects of leukotrienes at receptors in the airways which decreases the early and late responses to allergens Reduce bronchoconstriction, inflammation and mucus production

Question 29

What are indications for leukatriene receptor antagonists?

Answer 29

Prophylaxis for non-acute asthma

Question 30

What is rifampcin?

Answer 30

TB therapy

Question 31

What is isoniazid?

Answer 31

TB therapy

Question 32

What is ethambutol?

Answer 32

TB therapy

Question 33

What is pyrazinamide?

Answer 33

TB therapy

Question 34

What is the treatment plan for TB?

Answer 34

All 4 TB drugs for 2 months Then rifampicin and issoniazide for a further 4 months

Question 35

What are side effects of rifampicin?

Answer 35

Orange irn bru tears/urine Induces liver enzymes Hepatitis

Question 36

What are side effects of isoniazid?

Answer 36

Hepatitis Peripheral neuropathy

Question 37

What are side effects of ethambutol?

Answer 37

Optic neuropathy

Question 38

What are side effects of pyrazinamide?

Answer 38

Gout