Surgical management of lung cancer Flashcards
What % of lung cancer cases are linked to asbestos exposure?
4%
What are the symptoms of lung cancer?
Cough Fatigue weight loss SOB haemoptysis chest pain recurrent chest infections wheeze hoarse voice dysphagia fever face swelling
What are the symptoms of metastatic lung cancer, in addition to general symptoms?
bone pain spinal compression limb weakness paraesthesia bladder/bowel dysfunction vomiting dizziness headache ataxia focal weakness thrombosis
Paraneoplastic effects of lung cancer:
Hyponatraemia SIADH Anaemia Hypercalcaemia Parathyroid hormone related protein
What are the clinical signs of lung cancer?
Finger clubbing Lymphadenopathy Horners syndrome from Pancoast tumour Superior vena cava obstruction Hepatomegaly Skin nodules Lung signs
Where are large cell tumours likely to found?
Anywhere in the lungs
Where are the adenocarcinoma tumours likely to be found?
Develop from mucus producing cells found on the outer edges of the lungs
Where are the squamous tumours likely to be found?
Originiate from epithelium of the airways, mainly affect the centre of the lungs
Where are SCLC tumours likely to be found?
Larger airways and in major bronchus wall
What imaging can be used when investigating lung cancer?
CXR CT PET Isotope bone scan Head CT
What techniques can be used for tissue diagnosis of lung cancer?
Bronchoscopy EBUS Image guided lung/liver biopsy Fine needle aspiration Excision of cerebral metastases Boe biopsy Mediastinoscopy/otomy Surgical excision biopsy
What % of patients undergo surgery?
18%
What drugs are suggested for squamous cell carcinoma?
Cisplatin or gemcitabine
What drugs are suggested for small cell carcinoma?
Cisplatin or etoposide
What drugs are suggested for adenocarcinoma?
Cisplatin or pemetrexed
