surgery Flashcards

1
Q

Nasolabial flap artery

A

angular artery

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2
Q

LA onset determined by which compoenent

A

aromatic ring

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3
Q

LA amine determines

A

duration action

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4
Q

LA no epi duration of action

A

30-60 min

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5
Q

max LA without epi

A

max 4.5mg/kg

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6
Q

max LA with epi

A

+epi 7 mg/kg

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7
Q

how b-blockers affect LA levels

A

increase

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8
Q

maximum vasoconstriction epinephrine time

A

15 min

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9
Q

commonest cause Allergy in LA

A

paraben

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10
Q

which LA should, not be use in children

A

prilocaine

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11
Q

LA with vasoconstrictor( no epine) effect

A

cocaine

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12
Q

is epinephrine in nerve block vasoconstricitve

A

not

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13
Q

sodium bicarb : 1% lidocaine ratio

A

1:10( reduce sting/but shelf life),

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14
Q

Max dose of lidocaine+ epi in tumescent anesthesia

A

50mg/kg,

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15
Q

ESLD appropriate anesthetic

A

use benzocaine- renal metabolis

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16
Q

cosmetic unit :Cutaneous lip- chin

A

mental crease;

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17
Q

is nasal tip cosmetic unit

A

NOT

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18
Q

FTSG Not on

A

cartilage!,

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19
Q

FTSG size must be

A

• 25% larger

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20
Q

FTSG contract by% from donor site

A

15%

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21
Q

Alopecia neoplastica-

A

breast CA

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22
Q

Imiquimod fda indications

A

FDA AK sBCC < 2cm body NOT face scalp anogenital)

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23
Q

SCC prognosis- worst –

A

depth invasion> 4mm, size > 2cm

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24
Q

Wound healing collagen first deposited

A

type 3

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25
Q

Botox A pain worsened by

A

preservative free saline

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26
Q

Avoid Facial nerve injury byundermining which plane

A

undermine subQ fat

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27
Q

vertical skin tension lines

A

Scapula

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28
Q

avoid benzocaine, parabens sulphonamide thiazide diuretic

A

PPD allergy-

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29
Q

post surgery Dermabrasion

A

6w

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30
Q

IE prophylaxis

A

60 min before

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31
Q

NO need IE prophylaxis

A

for ASD

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32
Q

lateral canthus  infraorbital rotation

A

Mustarde flap

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33
Q

Lip defects-

A

primary closure

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34
Q

Eyelid defect- - wound contraction

A

2 intention CI

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35
Q

MCW melanoma cocktail –

A

monclonal ab MART1 melan A tyrosine , SLN bx, micromets detection

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36
Q

Trapdoor deformity-

A

nasolabial flap

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37
Q

Acne scarring – laser ro use

A

ND yag( 1064 nm) greatest depth penetration

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38
Q

dorsal nasal rotation flap

A

Riger –

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39
Q

glabellar mid forehead

A

Supratrochlear-

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40
Q

1st absorbed- what suture

A

catgut 7-14d

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41
Q

Polyglactin type of suture

A

vicryl

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42
Q

polyglycolic acid –absorption

A

90 days

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43
Q

absorbable monofilament 180d

A

Polydioxanone PDS-

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44
Q

Antiptosis subdermal suspension- type of thread

A

polypropylene thread

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45
Q

periorbital fat pad

A

Phosphatidylcholine

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46
Q

Procerus-

A

inferomedial

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47
Q

alpha tocopherol

A

Major antioxidant

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48
Q
  • cd4 lymphocytopenia
A

Skin cancer risk

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49
Q

salicylic acid lactic ethanol resorcinol no neutralisation

A

Jessner peel-

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50
Q

supf temporal facial artery-labial angular, maxillary posterior auricular occipitalare branches of ?

A

ECA-

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51
Q

ICA branches EXCEPT

A

angular artery

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52
Q

Baker Gordon

A

phenol

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53
Q

phenol

A

arrhythmia liver/renal failure

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54
Q

phenol *epidermolytic penetration

A

deep peel croton oil

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55
Q

Erbium yag/co2( 10600nm) which part ocular damage

A

aqueous- cornea

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56
Q

PDL(585nm)ndyag alexandrite ruby ocular damage

A

retinal pigment,

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57
Q

Alexandrite KTP ruby Ndyag diode - what medium

A

solid medium

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58
Q

which laser has liq medium

A

PDL

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59
Q

argon co2 krypton cu vapour all require what type media?

A

Gas media –

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60
Q

Erbium- post- Cx

A

milia

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61
Q

Reticulate erythema

A

diod laser

62
Q

Organ transplant chemoprotective agent

A

rapamycin

63
Q

shorten length excision

A

M plasty

64
Q

no inflammatory response , show up on dental xrays

A

Radiesse- hydroxyhapatite

65
Q

Infraorbital botox- adverse event

A

festooning

66
Q

Thermage complication –

A

lipoatrophy

67
Q

HIV lipoatrophy,longest DOA, FDA

A

Sculptra

68
Q

blue nodules caused by which filler

A

Restylane- hyaluronic acid-

69
Q

CI in anaphylaxis low allergic , duration 6-12 m

A

Restylane- hyaluronic acid-

70
Q

Fibroblast harvestomh – dermal augmentation

A

Isolagen-

71
Q

electrocautery, • Electrosurgery

A

NOT

72
Q

scalpel form of electrocautery

A

shaw

73
Q

Follicular unit hair transplantation

A

2-3 months post implantation

74
Q

EMPD- mohs-

A

CK7

75
Q

Which Tattoo pigment allergic eczematous granulomatous pseudolymphomatous- lichenoid ,

A

mercuric sulphide

76
Q

cadmium sulphide causes phototoxic reaction.

A

phototoxic reaction –

77
Q

Strength wound- 2w

A

-5%,

78
Q

Strength wound- • 1m

A

-50%

79
Q

Strength wound- 6m

A

70%,

80
Q

Iodine/benzakonium chloride-

A

ACD

81
Q

Z plasty bilobed rhombic nasolabial flap

A

Transposition flaps

82
Q

AT type of flap

A

Advancement-

83
Q

What flap can decrease wound tension

A

Z plasty –

84
Q

helix lobule innervation

A

Greater auricular nerve

85
Q

tragus innervation

A

Auriculotemporal( mandibular branch trigeminal

86
Q

PWS- which laser

A

586 nm PDL

87
Q

ALA PDT

A

protoporphyrin IX

88
Q

Serotonin action in wound healing

A

Cross link collagen molecules

Stimulate fibroblast prolifration

89
Q

Histamine kinin prostaglandin complement common action in wound healing

A

Increase vascular permeability

90
Q

Which chemical mediator also sensitise pain receptor and increase synthesis GAGS

A

Prostaglandin

91
Q

Which chemical mediator increases phagocytosis enhance bacterial lysis mast cell and basophil activation in wound healing

A

Complement

92
Q

Partial thickness wounds difference full thickness wound via mechanism of wound healing

A

PT- re epitheliazation from both wound edges and adnexal structures
Vs FT- only from wound edges

93
Q

Defeciency nidogen 1, TGFb, superoxide dismurase IL6, TLR3 all cause

A

Delayed wound healing

94
Q

Mice lacking MMP demonstrate

A

Accelerated wound healing

95
Q

For what wound size does primary intention healing deonstrate superior result

A

For wounds >8 mm

96
Q

3 phases of wound healing are

A

Inflammatory
Prolifeerative
Remodeling

97
Q

Components of the provisional matrix ?

A

Vitronectin, thrombospondin 1/2, tenascin, GAG, proteoglycans, collagen 3/6

98
Q

Compenents of remodelled collagenous scar

A

Collagen 1

99
Q

First extracellular matrix deposited in wound space

A

Fibrin clot

100
Q

Name of transmembrane receptors that recognise and bind to ECM proteins

A

Integrin

101
Q

Migration of keratinocytes over wound bed regulated by

A

Keratinocyte growth factor and hepatocyte growth factor

102
Q

Classic marker of activated keratinocytes

A

K6 k16

103
Q

What event marks irreversible terminal differentiation of keratinocytes

A

Process profilaggrin into filaggrin

104
Q

Location of multipotent stem cells

A

Stem cells in bulge region of outer follicular root sheath

105
Q

What causes fibroblasts to differentiate into protomyofibroblast

A

Mechanical stress

106
Q

What causes protomyofibroblasts into myofibroblast

A

TGFb1

107
Q

Protomyofibroblasts characterised by expression of

A

Fibronectin variant ED-A

108
Q

Recombinant growth factor approved for topical treatment of diabetic foot ulcer

A

PDGF -BB

109
Q

What dressing for highly exudative wound

A

Alginate

110
Q

Part of nail that forms dorsal superficial surface

A

Proximal nail matrix

111
Q

What is o2 requirement for optimal fibroblast proliferation

A

Hypoxia

112
Q

What part of nail matrix is responsible for ventral deep surface of nail ?

A

Distal nail matrix

113
Q

Part of nail matrix responsible for lunula?

A

Distal 1/3 matrix

114
Q

Nail bed sits directly over

A

Periosteum

115
Q

Orientation of nail matrix biopsy ?

A

Horizontal

116
Q

Orientation of nail bed biopsy

A

Vertical

117
Q

Depth of nail biopsy

A

Down to periosteum

118
Q

Location of biopsy of melanonychia

A

Distal nail matrix

119
Q

Nail matrix excision results in what changes to nail plate?

A

Thinner nail plate, thickness proprtional to length of matrix

120
Q

Ideal excision of nail matrix orientation and location? For minimal nail dystrophy?

A

Horizontal orientation in distal nail matrix

121
Q

TCA 30% is a ? Peel

A

Superficial

122
Q

antiviral prophylaxis given for which chemical peels

A

medium and deep

123
Q

TCA 30% is what level of peel?

A

supeficial

124
Q

jessner’s solution consist of ?

A

salicylic/lactic acid, resorcinol, ethanol

125
Q

88% phenol is an e.g. of ?

A

medium chemical peel

126
Q

2 e.g. of deep chemical peel

A

bakergordon, TCA > 50%

127
Q

glycolic acid 70% alone is what level peel??

A

superficial

128
Q

1)anything containing 35% TCA

or 2) 88% phenol are what level chemical peel

A

medium level

129
Q

content of baker gordon

A

phenol, croton oil. liq hexachlorophene, distilled water

130
Q

medium depth peel at what level ?

A

papillary dermis

131
Q

MOA of BTX inhibit Ach release?

A

cleave SNARE complex

132
Q

BTX type A light chain cleaves what protein?

A

snAp25

133
Q

BTX type B light chain cleaves what protein?

A

synaptoBrevin, VAMP protein

134
Q

Botox effective for what type facial lines?

A

dynamic not static

135
Q

which type botox FDA approved for labellar rhytides and hyperhidrosis

A

A

136
Q

pregnancy category of Botox

A

C

137
Q

How to prevent eyelid ptosis when injecting botox ?

A

1 cm above orbital rim

138
Q

adverse effect of injecting orbicularis oculi for crows feet when patient is smiling?

A

ptosis of upper lip–> ipsilateral zygomaticus complex

139
Q

Monsel’s solution should be avoided

in the setting of

A

biopsy specimens of pigmented

lesions

140
Q

split thickness skin graft ooze
What is an ideal agent to place in the wound before
the nonstick dressing?

A

gelatin ,hygroscopic, hemostasis by
a 3-dimensional meshwork within which
platelets can aggregate to form a clot

141
Q

ideal for patients who are undergoing

long-term anticoagulation therapy to obtain hemostasis between stages that is easily removed

A

Hydrophilic polymer, efficacy of WoundSeal does not depend on the body’s clotting

142
Q

TGFb1 and TGFb2 expression leads to ? scarring

A

TGFb1 and TGFb2 expression leads to in-creased scarring

143
Q

TGFb3 expression leads to ?scarring

A

reduced scarring

144
Q

Proinflammatory cytokines such as? enhance scarring

A

interleukin-6 IL-6 and IL-8 enhance scarring

145
Q

antiinflammatory cytokine

? decreases the amount of scar tissue

A

IL-10

146
Q

In wound healing , Homeobox b13, the Wnt signaling pathway, early growth response-1, and platelet-derived growth factor all favor

A

fibroplasia

147
Q

onychomatricoma coexistingprocess?

A

Onychomycosis

148
Q

Co2 laser Potential disadvantages

A

includerisk of burns to the face and exaggerated removal oftissue with cartilage exposure.

149
Q

The Shaw knife has been particularly useful

A

b. debulking large tumors

150
Q

Lymphatic drainage of the eyelids is by the

A

.preauricular and submandibular nodes

151
Q

In performing operation on the lower eyelid,which branch greatest
risk of trigeminal injury?

A

d. Lacrimal