infectious Flashcards
1
Q
primary effusion lymphoma,
A
KS
2
Q
HHV 8 semen %HIV
A
20%
3
Q
woods lamp copyroporphyringen
A
erythrasma
4
Q
Valacyclovir-in immunosuppressed
A
TTP
5
Q
paravaccinia
A
milkers nodule
6
Q
xenopyxella cheoplas
A
endemic murine typhus
7
Q
GPRwoolsorter
A
anthrax,
8
Q
widened mediastiunum,
A
inhalational anthrax
9
Q
lethal toxin virulence cytokine
A
TNF-a
10
Q
child erythema migrans Rx
A
amoxicillin
11
Q
Leprosy cytokine
A
-il2
12
Q
Nhl,mixed cryoglobinemia link with virus
A
HCV
13
Q
patchy lung infiltrate eosinophilia is result of
A
larva migrans
14
Q
•papillomatosis cutis carcinoides causative virus
A
hpv 11-
15
Q
negative weil felix
A
rickettsial pox
16
Q
primary syphilis most sensitive markers
A
fta abs
17
Q
hutchinson teeth is a feature of
A
late congenital syphilis
18
Q
human body louse carries what type typhus
A
epidemic typhus
19
Q
secondary syphillis- ?w after chancre
A
3-12w
20
Q
SIADH is a feature of what type viral infection
A
ramsay hunt-
21
Q
bartonella hensalae rx
A
erythromycin
22
Q
c5 deficiency predisposes to
A
meningococcemia
23
Q
seabthers pattern of distribution
A
-areas covered
24
Q
which medications has side efect edema itching arthralgia
A
dimethylcarbamazine-
25
onchocerciasis-Rx
dimethylcarbamazine-
26
whitmore disease
burkholderia
27
chocolate. Agar,
gonorrhea,
28
-NNN Novy-MacNeal-Nicolle (NNN) medium,
leishmaniasis( espundia),
29
pentavalent antimony,
leishmaniasis-
30
leishmaniasis- vector
sandfly,
31
STD lgv-
proctocolitis
32
%-hiv hairy tongue
33%
33
of all sct-,? % first year zoster
| •
70%
34
HSV HLA link
HLAB15
| herpes assoc EM
35
congenital varicella syndrome-
1st 20w
36
michelis gutmann bodies stain
-von kossa
37
HPV 60-
ridged wart,
38
focal epithelial hyperplasia
HPV,
39
HPV 7
butchers warts ,
40
Hpv5,8,9,
epidermodysplasia verruciformiis-
41
HPV 6/11,
genital wart
42
hpv13/32
hecks disease
43
s aureus pseudomonas, e coli
uncontrolled HIV
44
fish handlers finger
strep iniae
45
buschke lowenstein
Hpv6
46
epithelioma cuniculatum, ,
sole-HPV
47
miculicz cell foamy macrophages
klebsiella
48
klebsiella rx
ciprofloxacin
49
erysipeloid rx
penicillin
| •
50
acrodermatitis chronica atrophicans
borrelia afzelii •
51
reduviid bug
chagas
52
incubation IMO
3-7 w
53
verruga oerunialiglis vector
sandfly
54
>20 outside dermatome,
disseminated
55
PAN hep? %
7-8%
56
-roseola infantum
HHV6
57
hemophilus ducreyi chancroid
school of fish
58
camylobacterium granuloma
granuloma inuinale -
59
onychomadesis cause
enterovirus
60
strep moni, penicillin
rat bite fever,
61
groove sign LN
LGV
62
oroya fever /carrions disease superfinfection
salmonella
63
papillma virus - children
stridor
64
rhabsomyosarcoma LCH hemolytic disease TORCH
blueberry muffin
| •
65
photochromogen
M kansaii
66
fever central eschars
rickettsial pox
67
ssDNA
parvovirus
68
verrugua peruana
bartonella bacilliniformis
69
E infectiosum
parvovirus
70
gamma favre bodies
LGV
71
R prowazeki
epidemic typhus
72
orf rx
Self resolving,
73
eczema vaccinatum rx smallpox vaciine
• IVIG-
74
smallpox vaciine efficacy
vesicle 4 cm erythema
75
purpura fulminans bacteria
gpA strep
76
bartonella bacilliniformis vector
lutz sandfly
77
enterotoxin B
TSS
78
calabar swellings
loiasis-
79
pregnant lyme dz rx
amoxiciin
80
MCV in HIV CD4
CD4<100
81
ixodes daminiii
vector NW USA lyme dz
82
b duttoni,
tick born relapsing
83
MCV subtyp HIV
MCV 2
84
MCV MOA HIV
evades IL18
85
zoster ? %p yr HIV
3%
86
colarado tick fever causative agent
virus
87
jarisch herxheimer cytokine
TNF-a
88
M marinum RX
minocycline
| cipro doxy
89
mortality untreated M marinum
20%
90
brucellosis
GNR
91
pediculosis humanis corporis
epidemic typhus
92
botrymycosis suppurative
S aureus
93
% asymptomatic congenital CMV
90
94
loiasis vector
mango fly
95
rickettsial pox vector
mouse
96
iv penicillinase resistant penicillin
SSSS
97
deafness MR
congenital CMV
98
hi-CAMP
orf
99
palatal petechiae,
EBV
100
8-r old common baceria
Hib
101
Exanthem subitum
HHV6
102
safety pin intracytlasmic inclusions,
Granuloma Inguinale
103
non menstrual TSS
enterotoxin B /C
104
winterbottom sign
african trypansosomiasis
105
Dapsone Clofazamine Rifampicin
leprosy
106
rabies diagnostic biopsy location
neck
107
migratory eosinophilic panniculitis
gnathostomatiasis fish
108
HBsAg ; anti-HBc ;anti-HBs;
negative positive positive
Immune due to natural infection
109
HbsAg anti-HBcIgM anti-HBc anti-HBs
positive positive. negative. negative
Chronically infected
110
massive number of bee stings can result in multiple organ failure because the venom is rich in
phospholipases
111
Fire ant venom contain
Solenopsin A
112
Cantharidin in ‘‘blister’’ Coleoptera (beetles) cause vesi-cles and bullae by activation of
neutral serine proteases, which cause degeneration ofdesmosomes
113
the main sign of injury of Millipedes
is hyperpigmentation
| Millipedes have lateral glands, instead of fangs, which contain cyanide and quinones;
114
The brownrecluse spider bite can cause skin necrosis (ie, loxoscelism via
sphingomyelinase D which can be
| treated with antivenomand/or sulfones.
115
What arthropod contact can result in dermatitis and conjunctivitis via allergic reactions, which can be treated with topical corticosteroids and oral antihistamines.
Tarantula contact with body bristles
116
What bites cause pain and erythema via metalloproteases, which canbetreatedwith cold compresses and analgesics
Centipede
117
Brown recluse spiders can cause extensive
| skin necrosis and acute renal failure via
sphingomyelinase D; therapy is with antive-nom (antivenin) and/or sulfones
118
Lower limb cellulitis is a common
| infection, primarily caused by
streptococci, which often reside in the interdigital toes space
119
For LL cellulitis, what significantly shortens the duration of illness and
may reduce episodes the frequency of
subsequent flares?
A brief course of oral corticosteroids
120
carcinoma erysipelatoides has involved the lower limb with malignancies of
the bladder and prostate.
121
During transmission, borrelial surface lipo- proteins are altered; OspA
downregulated,
122
During transmission, borrelial surface lipo- proteins are altered; OspC and DbpA are
upregulated
123
Lyme disease : The most effective transmission occurs ?hours after the onset of tick attachment
48 to72 hours
124
Lyme disease is evident in three stages,
The ? stage involves host-wide spiro-chetal dissemination and further skin mani-festations, with or without neurologic, joint,and cardiac involvement
second stage
125
Lyme disease is evident in three stages, ? which includes erythema migrans
first
126
Lyme disease ? Stage manifests with persistent neurologic symptoms, recur-rent arthritis, or acrodermatitis chronica atrophicans
The third stage
127
Lyme disease: Central nervous system invasion usually occurs without the production of
intrathecal inflammatorychemokines
128
Lyme disease: Initial serologic diagnosis, when
| indicated, requires a two-tiered system,with
an enzyme-linked immunosorbent assay followed by Western blot.
129
lyme disease treatmemt dor children under 8 years of age with early disease,
an excellent approach is 50 mg/kg per day of oralamoxicillin, divided into three doses, and not ex-ceeding 500 mg per dose
130
The causative agent of STARI
remains uncertain ,
131
southern tick associated rash illness (STARI) tick
Lone Star tick (Amblyomma americanum)
132
. associated with verrucae, lym-phedema, immunodeficiency, and a history of infections and skin cancer
GATA2 deficiency
133
Larva currens vs cutaneous larva migrans,
Larva currens is a hypersensitivity reaction cutaneous
| manifestation ofStrongyloides and should be distinguished fromcutaneous abortive larva human migrans,animalhookworm.
134
best treatment for tungiasis
Surgical excision
135
chromoblastomycosis most common etiologic agent is
F pedrosoi
136
HIV-infected patients cryptococcus presentation
molluscum-like lesions,
137
Cryptococcus organ transplant recipients present more commonly with
lesions on the extremities that mimic bacterial cellulitis.
138
Rx cryptococcus with central nervous symptoms or dissemination?
Amphotericin B with or without flucytosine
139
Zoster most common vertebral dermatomes are
| most common cranial nerve dermatome is
T5 and T6,
| Ophthalmic Division of the trigeminal nerve.
140
the treatment for herpes zoster include all of the following valacyclovir
a. A more convenient dosing schedule
b. Greater bioavailability
c. Higher effective plasma levels
d. Lower daily dose
141
Which form leprosy high levels ofinterferon gamma (IFN-g), interleukin 2 (IL-2),TNF
tuberculoid disease manifesta predominantly Th1 response with high levels ofinterferon gamma (IFN-g), interleukin 2 (IL-2), TNF
142
What form leprosy demonstrate higher levels of Th2-associated cytokines (IL-4, IL-5, and IL-10) and low levels of IL-2and IFN with a predominance of CD8 cell
Lepromatous
143
Mucormycosis Rhinocerebral infections and orbital cellulitis are most common in patients .
with diabetes
144
Mucormycosis Rx
AmphotericinB, posaconazole , surgery
| traconazole/ voriconazole/aspofungin/ flucytosine ineffective
145
for treating mucormycosis. ?is synergistic when used in conjunction with pos-aconazole.
caspofungin, an echinocandin class antifungal
146
iron chelator deferoxamine can also increase the risk of mucormycosis infection because it
acts as a siderophore,providing iron for fungal growth
147
Previous exposure to ? has been shown to be an independent risk factor to mucormycosis
Voriconazole
148
Phaeohyphomycosis is typically follows
traumatic implantation of the fungi by a wood splinter or a thorn prick.
149
fungal infections caused by a variety of naturally pigmented fungi, including Exophiala jeanselmei, Exophiala spinifera, and Wanigella dermatitidis.
Phaeohyphomycosis
150
Unrelated species do not need to be treated for human scabies mites?
Animals can also become infected with scabies. However, the mite that colonizes animals is different from the type that affects humans.
151
erythema migrans test
Polymerase chain reaction of the skin biopsy specimen
Amplification of B burgdorferi DNA by polymerase chain reaction studies is the most useful tool for the detection of bacterial DNA from skin biopsy specimens and synovial or cerebrospinal fluid. It is said to be positive in ≤90% of erythema migrans biopsy
152
What stage ? ArgylleRobert-son pupil.
tertiary syphilis is the ArgylleRobert-son pupil.
153
Orf caused by
Orf is one of several relatively uncommon cutaneous infections caused by zoonotic poxviruses
154
the most specific diagnosis for infection with M leprae.
Polymerase chain reaction studies amplify sequences of target DNA
155
most sensitive and specific technique for leishmaniasis .
Polymerase chain reaction
156
? are the mostdefinitive tests in early syphilis and
| Clinical specimens, taken from ?
Darkfield microscopy direct fluorescent antibody testing are the mostdefinitive tests in early syphilis and are able todemonstrate
Clinical specimens, takenfrom lesional exudates, are the most amenable tothis type of testing
