Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 3 Oral Biology > Surface coatings of the tooth > Flashcards

Surface coatings of the tooth Flashcards

You may prefer our related Brainscape-certified flashcards:
AP® Biology flashcards Biology 101 flashcards
1
Q

what makes up nasmyths membrane

A

reduced enamel epithelium + primary enamel cuticle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

2 cell layers that make up the reduced enamel epithelium

A

ameloblasts (flattened, post maturation stage)
stratum intermedium
(both parts of the ENAMEL ORGAN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

define primary enamel cuticle

A

basal lamina associated with reduced enamel epithelium and the newly formed enamel surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what produces the primary enamel cuticle

A

mature ameloblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

describe nasmyths membrane and when it is present

A

covering over tooth once enamel has formed, pre eruption only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

describe what happens in reduced enamel epithelium during eruption

A

stratum intermedium divides –> REE thickens to meet overlying oral epithelium= PRIMARY JUNCTIONAL EPITHELIUM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what joins reduced ameloblasts to the basal lamina (primary enamel cuticle)

A

hemidesmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what forms junctional epithelium

A 
mostly REE (stratum intermedium)
small amount from oral epithelium (determined by cytokeratin expression patterns)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how/ what does primary epithelium change in to

A

moves down tooth surface as tooth erupts –> JE rests at last apical mms of enamel = SECONDARY JUNCTIONAL EPITHELIUM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
function of JE
what happens when it fails
A

BARRIER seals oral environment from underlying connective tissues (forms collar whole way around tooth)
(breach –> periodontal disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

where is JE in relation to gingival sulcus

A

top of JE –> bottom of gingival sulcus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what happens to JE position in periodontal disease

A

moves down tooth –> attaches to cementum instead of enamel –> increased length of sulcular epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

where is junctional epithelium thickest

A

nearest the oral cavity

may only be 1-2 cells thick nr cementum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

structure of junctional epithelium

A

stratified, non-keratinised epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

4 reasons junctional epithelium is unique

A
  • has 2 basal lamina
  • wide intercellular spaces (modified desmosomes, no tight junctions)
  • only barrier that is not KERATINISED (eg compared to skin)
  • best turnover of any tissue; all cells in JE turnover, not just basal layer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

location of JE’s 2 basal lamina

A

UNIQUE; DOESNT MATCH:
internal basal lamina IBL –> Enamel
External basal lamina –> Connective tissue

17
Q

how does JE basal lamina attach to enamel surface

A

hemidesmosomes

18
Q

how does the junctional epithelium attach to the IBL

A

DAT cells (directly attaching cells)

19
Q

what is bullous pemphigoid protein

A

one of the proteins that attaches JE DAT cell to IBL

20
Q

describe/ explain bullous pemphigoid disease

A

autoimmune condition –> attack on bullous pemphigoid antigens –> cells separate from basal lamina –> fluid filled ulcers on skin and oral mucosa

21
Q

explain the funnel effect

A

proliferative cell layer next to connective tissue –> new cells in JE–> migrate coronally due to 3:

  • wide intracellular spaces
  • no tight junctions
  • modified desmosomes
  • -> desquamation of cells to gingival sulcus = GINGIVAL CREVICULAR FLUID
22
Q

evidence that funnel effect helps prevent infectino

A

neutrophils (and nerve endings) also present in JE interceullular spaces (migrating up for desquamation) in dogs and rats

23
Q

compare rate of turnover of JE to oral mucosa

A

50-100x faster

24
Q

4 ways JE prevents infection 8

A

DNT Let Fucking Paedos Near Children

  • Desmosomes modified, less than other tissues
  • Neutrophils intercellular (dogs/ rats) (GCF, funnel effect)
  • Turnover is rapid
  • Lysosomal bodies in JE cells (acid phosphatase activity, engulf bacteria and cellular debris)
  • Funnel effect (bidirectional flow of GCF and cells as antimicrobial defense mechanisms)
  • Physical barrier via intercellular adhesion molecules
  • Nerve endings modulate JE cells and neutrophils
  • Cytokine expression
25
Q

where do nerve cells in JE originate

A

connective tissue

26
Q

what do JE nerve endings contain 2

A
  • substance p

- calcitonin gene related peptide (CGRP)

27
Q

what moves in each direction of bidirectional flow of GCF

A

out: neutrophils/ PMNs, JE cells, fluid exudate from connective tissue
in: bacteria from oral cavity/ enamel surface

28
Q

what is region where most bacteria invading JE come from and why

A

enamel in gingival sulcus- difficult to access w toothbrush

29
Q

rate of flow of PMNs/ minute through JE

A

30,000

30
Q

where do neutrophils/ PMNs etc (outward GCF flow) originate

A

connective tissue around tooth

31
Q

how do the intercellular spaces enlarge

A
  • rupture of (modified) desmosomal junctions

- distended by PMNs and fluid

32
Q

how often are no inflammatory cells found in JE

A

never/ vv rare

33
Q

amount of GCF found in health

A

none/ very little

34
Q

4 sources of GCF constituents + examples

A

1 IN ORAL CAVITY: microbial plaque (LPS, enzymes, metabolic end-products)
3 IN CONNECTIVE TISSUE:
-host inflammatory cells (PMNs, leukocytic enzymes, lactoferrin, lysozyme)
-host tissue (collagens, proteoglycans, matrix proteins
-serum derived factors (IgGs, complement, cytokines, eicosanoids, prostaglandins, leukotrienes)

35
Q

formation of acquired enamel pellicle

A

post eruption: REE and underlying primary cuticle (Nasmyth’s membrane) break down by attrition/ abrasion –> acquired enamel pellicle forms in its place

36
Q

2 layers/ contents of AEP

A
  • Acellular base layer (protective proteins strong bind to HA)
  • Organic matter from 3: saliva (statherin, proline-rich proteins), bacteria, GCF
37
Q

function of AEP 2

A
  • lubricating layer for efficient mastication

- prevents oral tissue dehydration

38
Q

how does plaque form

A

oral bacteria adhere to AEP

39
Q

how does dental biofilm form

A

AEP + plaque

Year 3 Oral Biology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions