Eruption Revisited Flashcards
5 phases of eruption
- intraosseous
- mucosal penetration (teething)
- pre-occlusal eruption (supra-osseous)
- post-eruptive movements
- overeruption of unopposed teeth
3 functions of post eruptive movements
- accommodate growing jaws
- compensation for occlusal wear
- accommodate interproximal wear
which phase(s) of eruption is the fastest
after mucosal penetration
processes required for eruption
-mechanism to generate eruptive forces
–> eruptive forces translated in to movement through the surrounding tissue
+ remodelling of periodontal tissues to maintain functional integrity/ support of tooth
name of current theory of tooth eruption
alveolar bone modelling
what cells probably organise eruption pathway
enamel organ cells of follicle
name of people who demonstrated that dental follicle is important to tooth eruption
Marks & Cahill
what phase of eruption is an example of alveolar bone modelling
intraosseous
is bone resorption during eruption controlled by mechanics or genetics? explain
genetics
osteoclast activity does NOT depend on tooth movement
2 molecules that induce osteoclastogenesis
- MCSF1 (macrophage colony stimulating factor 1)
- MCP-1 (monocyte chemotactic protein 1)
molecule that regulates osteoclastogenesis
-RANKL (receptor activator of NFkB ligand, TNF family. interacts with membraene-bound RANK receptor on pre-osteoclast surface
role of CSF1
chemokine. required for growth and differentiation of pre-osteoclasts, up-regulation of RANK
role of OPG (osteoprotegrin)
PROTECTS bone: inhibits osteoclast formation by preventing cell-cell signalling
how are osteoblasts formed
fusion of mononuclear cells –> multinucleated osteoclasts
location of osteoclasts, osteoblasts and relevance
osteoclasts: coronal end of follicle
osteoblasts: base of crypt
- -> tooth must erupt coronally as bone has been removed, and bone is forming apically
