**Summaries** Flashcards
MEN 1
Pituitary Adenoma
Parathyroid Hyperplasia
Pancreatic Islet Cell Tumors (gastrinoma, insulinoma)
“I pee”
MEN 2a
Medullary Thyroid Cancer (Calcitonin)
Parathyroid Hyperplasia (Calcium)
Pheochromocytoma
“II ac”
MEN 2b
Medullary Thyroid Cancer
Marfanoid Habitus/Mucosal Neuromas (lips, tongue, eyelids)
Pheochromocytoma
“Abe Lincoln”
Organisms that Cause Bloody Diarrhea
SEECSY
- salmonella (pea soup)
- e.coli 0157:H7 (HUS: ARF, thrombocytop, hemolytic anem)
- entamoeba (protazoa)
- campylobacter (s - GB)
- shigella (HLAB27 & daycare)
- yersinia enterocolitica (like appendicitis)
Organisms that Cause Watery Diarrhea
VRECS Gi
- vibrio cholera
- rotavirus/norwalk virus
- e. coli (enterotoxigenic#1 cause of traveler’s diarrhea)
- cryptospordium (#1 cause of recreational diarrhea; India ink stain)
- s. aureus/b. cereus (food poisoning)
- giardia
Chocolate Cyst
Endometriomas
Dermoid Cyst
Calcification #1 Cause of Torsion
OCPs protect against
- endometrial cancer
- ovarian cancer
- rheumatoid arthritis
OCPs increase risk of
-breast cancer
What increases risk of endometrial cancer?
- leiomyomas
- PCOS
- tamoxifen (decrease risk of breast cancer but increase risk of endometrial cancer)
Methotrexate for Abortion if
-mass
HIV and babies
25% if no tx
8% if antiretroviral tx and vaginal delivery
2% if antiretroviral and c-section
Good Pasture Syndrome
- alveolar hemorhage resulting in HEMOPTYSIS
- pulm-renal syndrome
Wegner Granulomatosis
- concomittant sinus and lung involvement
- rapid loss of renal function
Alport syndrome
hereditary
IgA Nephropathy
- hematuria after URI
- # 1 cause worldwide esp asia and south america
- IgA on biopsy
When to Start Dialysis
AEIOU
-Acidosis (esp if
Causes of Anion Gap Metab Acidosis
Calc = Na-(Cl+HCO3)
MUDPILES
Methanol Uremia DKA Paraldehyde, Propylene Glycol Infection, Iron, Isoniazid, Inborn Errors of Metab Lactic Acidosis Ethylene Glycol, Ethanol Salicylates
FeNa >2
Intrinsic renal failure
85% = ATN (muddy brown casts)
Proteus
Gram - rod lactose negative contains urease (forms ammonia = alkaline urine) if stones in Q = increased risk May cause struvite stones = staghorn
E.coli
Gram - rod
Lactose +
Oxidase -
Enterococcous
Gram + coccous
Klebsiella
lactose +
Oxidase -
(poorly controlled DM)
Warfarin
P450
CYP2D6
Warfarin Inhibitors
(stops metabolism = increased PT = need to decrease dose)
VICKS FACE All Over GQ (stops all the girls)
Valproate Isoniazid Cimetidine Ketoconazole Sulfonamides Fluconazole Alcohol (acute) Chloramphenicol Erythromycin (and other macrolides) Amiodarone Omeprazole Grapefruit Juice Quinidine
Warfarin Inducers
(increases metabolism = decreased PT = need to increase dose)
BS CRAP GPS (induces my rage)
Barbituates St. Johns Wort Carbamazepine Rifampin Alcohol (chronic) Phenytoin Griseofulvin Phenobarbital Sulfonylureas
Beta Blocker Selectivity
B1 selective = aa bm
-atenolol, metoprolol, acebutolol, bisprolol
B1 & B2
-propranolol, sotolol, timolol, nadolol, pindolol
a, B1 & B2 (labeled like superman)
-labetolol, carveidolol
Electrolyte Relationships
Mg, K, Ca down = Phos up
Hyperkalemia
peaked t waves prolonged PR (AV block) prolonged QRS
Hypokalemia
flat or inverted T waves, u waves
predispo to v-tach
increased risk of digoxin toxicity
Hypercalcemia
short QT
Hypocalcemia
long QT
Hypermagnesemia
long PR
wide QRS
Hypomagnesemia
tall T
Amiodarone Cardiac ADR
sinus brady and AV block
Ibulitide Cardiac ADR
torsades and QT prolong
Anti-CCP, RA
Rheumatoid Arthritis
ANCA
polyartertiits nodosa Wegners Granulomatosis Churgg Strauss IBD Primary Sclerosing Cholangitis
Anticentromeres
Limited Scleroderma
**assoc w/ crest
RF, ANA, AntiRo, AntiLa
Sjogrens
autoimmune; lip biopsy
Anti-DNA topoisomerase I aka Anti-Scl-70
Diffuse Scleroderma
Antihistone Ab
Drug induced SLE
isoniazid, procainamide, hydralazine, methyldopa, quinidine, chlorpromazine
Metabolic Syndrome
3 or more of:
1) Waist >102M >88F
2) TG >150
3) HDL 130/85
5) BG >110