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Clinical Pharmacology > Sulfonylureas (Oral Hypoglycemics) > Flashcards

Sulfonylureas (Oral Hypoglycemics) Flashcards

1
Q

Sulfonylureas

A

glipizide (Glucotrol & Glucotrol XL)
glimepiride (Amaryl)
glyburide (DiaBeta, Glynase, Micronase)

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2
Q

Therapeutic Uses
glipizide (Glucotrol & Glucotrol XL)
glimepiride (Amaryl)
glyburide (DiaBeta, Glynase, Micronase)

A

Type 2 diabetes

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3
Q

Mechanism of Action
glipizide (Glucotrol & Glucotrol XL)
glimepiride (Amaryl)
glyburide (DiaBeta, Glynase, Micronase)

A

Stimulate the pancreatic Beta-cells to release insulin. Enhances the cellular sensitivity to the insulin (makes the insulin work better)

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4
Q

Adverse Effects
glipizide (Glucotrol & Glucotrol XL)
glimepiride (Amaryl)
glyburide (DiaBeta, Glynase, Micronase)

A

Can cause mild hypoglycemia; weight gain

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5
Q

Administration
glipizide (Glucotrol & Glucotrol XL)
glimepiride (Amaryl)
glyburide (DiaBeta, Glynase, Micronase)

A

Taken orally typically with a meal (or 10-30 min before a meal)

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Clinical Pharmacology (11 decks)

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