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Clinical Pharmacology > Meglitinides (Glinides) (Oral Hypoglycemics) > Flashcards

Meglitinides (Glinides) (Oral Hypoglycemics) Flashcards

1
Q

Meglitinides (Glinides)

A

repaglinide (Prandin)

nateglinide (Starlix)

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2
Q

Therapeutic Uses
repaglinide (Prandin)
nateglinide (Starlix)

A

Type 2 diabetes

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3
Q

Mechanism of Action
repaglinide (Prandin)
nateglinide (Starlix)

A

Stimulate the pancreatic Beta-cells to release insulin

Similar chemical structure and mechanism of action to sulfonylureas. Considered
alternatives to sulfonylureas. Do not give WITH sulfonylureas – they are too similar

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4
Q

Adverse Effects
repaglinide (Prandin)
nateglinide (Starlix)

A

Can cause mild hypoglycemia; weight gain

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5
Q

Administration
repaglinide (Prandin)
nateglinide (Starlix)

A

Taken orally 15 – 30 minutes before or with a meal

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Clinical Pharmacology (11 decks)

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