Insulin

Question 1

Synthesized in the pancreas

Answer 1

Insulin

Question 2

Precursor of insulin

Answer 2

Proinsulin

Question 3

Byproduct of insulin

Answer 3

C-peptide

Question 4

Secretion is stimulated mainly by glucose.

Other stimulants = epinephrine, fatty acids, amino acids, ketone bodies

Answer 4

Insulin

Question 5

Promotes conservation of energy & increases cellular uptake of glucose, amino acids, & K+

Answer 5

Insulin

Question 6

Insulin is measured in…

Answer 6

“units” rather than “mg” or “mcg”

Question 7

In the United States, 2 concentrations are available

Answer 7

U-100 which has 100 units per ml

U-500 which has 500 units per ml

Question 8

U-500 is available in only one product

Answer 8

Humulin R

Question 9

8 units of insulin =

Answer 9

0.08 ml

Question 10

50 units of insulin =

Answer 10

0.5 ml

Question 11

Unopened vial stored in

Answer 11

refrigerator

Question 12

Discard after

Answer 12

expiration date marked on vial

Question 13

Avoid

Answer 13

freezing or heat

prolonged, direct sunlight

Question 14

For cloudy insulins

Answer 14

roll vial in hands gently to mix; do not shake vigorously

Question 15

Open vials:

Answer 15

Can be stored at room temperature

Levamir = 42 days, Lantus =28 days

Question 16

SC injections in

Answer 16

upper arms, thighs, and abdomen

Rotate injection sites

Question 17

Needless syringe that uses air to inject into skin

Answer 17

Jet injectors

Question 18

Pre-filled device with disposable needle

Answer 18

Pen injectors

Question 19

computerized device delivers a basal rate with

mealtime boluses by pressing a button

Answer 19

Portable Insulin Pump

Question 20

for emergency blood glucose reduction in hospital setting

Answer 20

Continuous insulin infusion

Question 21

Ultra Short / Fast Acting Insulin

Answer 21

Lispro Insulin (Humalog) 
Aspart Insulin (Novolog) 
Glulisine Insulin (Apidra)

Question 22

Short / Fast Acting Insulin

Answer 22

Regular Insulin
(Humulin R)
(Novolin R)

Question 23

Intermediate Acting Insulin

Answer 23

NPH [Isophane] Insulin
(Humulin N)
(Novolin N)

Question 24

Long /Slow Acting Insulin

Answer 24

Insulin Detemir (Levemir)
Glargine insulin (Lantus)

Question 25

Premixed Insulin Mixtures

Answer 25

NPH/Regular Mixture
(Humulin 70/30 & Novolin 70/30)

NPH / Regular Mixture (Humulin 50/50)

NPL / Aspart (Novolog Mix 70/30)

NPL / Lispro (Humalog Mix 75/25)