Succinylcholine

Question 1

Succinylcholine- class

Answer 1

Depolarizing neuromuscular blocker, paralyzing agent

Question 2

Succinylcholine - MOA

Answer 2

Bind to the receptors of acetylcholine at neuromuscular junction to cause skeletal muscle paralysis.

Question 3

Succinylcholine - Indications

Answer 3

Endotracheal intubation, to terminate laryngospasm and to promote muscle relaxation.

Question 4

Succinylcholine - Contraindications

Answer 4

Acute narrow angle glaucoma, penetrating eye injuries, inability to control airway or support ventilations, penetrating eye injury, burns or crush greater than 24 hours old, muscle wasting disease, malignant hyperthermia, hyperkalemia.

Question 5

succinylcholine - adverse reactions

Answer 5

apnea, malignant hyperthermia, arrhythmias, bradycardia, hypertension, hypotension, cardiac arrest, hyperkalemia, increased intraocular pressure, increased intracranial pressure, fasciculations.

Question 6

succinylcholine - drug interactions

Answer 6

Effects potentiated by oxytocin, beta blockers, and organophosphates. Diazepam may reduce duration of action.

Question 7

Succinylcholine - dosage and administration

Answer 7

Adult: 1-1.5 mg/kg IV, IO rapid
Ped: 1-1.5 mg/kg IV/IO rapid

Question 8

succinylcholine - duration of action

Answer 8

Onset: 1 min
Peak: 1-3 mins
Duration: 5 minutes

Question 9

Succinylcholine - Special considerations

Answer 9

If the patient is conscious, explain side effects prior to administration. Premedication with lidocaine may blunt any increase in intracranial pressure during intubation.

Question 10

succinylcholine- pregnancy category

Answer 10

C

Question 11

Succinylcholine - how supplied

Answer 11

200 mg in 10 mL vial