Calcium Gluconate

Question 1

Class

Answer 1

Electrolyte

Question 2

MOA

Answer 2

Increases cardiac contractility and may enhance ventricular automaticity. Stabilized cardiac cell membranes in hyperkalemia.

Question 3

Indications

Answer 3

Calcium channel-blocker OD (first line), beta blocker OD (second line), cardiac arrest, hypocalcemia, hyperkalemia.

Question 4

Contraindications

Answer 4

Pts taking Digoxin, leads to digoxin toxicity.

Question 5

Adverse reactions

Answer 5

Tingling sensation, nausea/vomiting, dry mouth, increased thirst.

Question 6

Drug interactions

Answer 6

May worse arrhythmias secondary to digitalis toxicity. Do not mix with or infuse immediately before or after sodium bicarbonate without intervening flushing.

Question 7

Dosage

Answer 7

Adult:
Hyperkalemia: 0.5-1g slow IV/IO push

Beta or calcium channel blocker OD: 3-6g IV/IO

Question 8

Duration of action

Answer 8

Onset: 5-15 mins
Peak: 3-5 mins
Duration: 15-30 mins. May go to 4 hrs depending on dose.

Question 9

Special considerations

Answer 9

Does not irritate the vessels as much as calcium chloride, it is a slightly weaker concentration.

Question 10

Pregnancy category

Answer 10

C

Question 11

How supplied

Answer 11

10% solution 10 mL vials, ampules or prefilled syringe (100mg/mL)