Ipratropium Bromide (Atrovent)

Question 1

Ipratropium Bromide- class

Answer 1

Anticholinergic, bronchodilator

Question 2

Ipratropium Bromide- MOA

Answer 2

Inhibits acetylcholine at bronchial smooth muscle receptors causing smooth muscle relaxation and bronchodilation. Decreases bronchial secretions.

Question 3

Ipratropium Bromide- Indications

Answer 3

Asthma, COPD

Question 4

Ipratropium Bromide-Contraindications

Answer 4

Hypersensitivity, allergy to atropine or peanuts.

Question 5

Ipratropium Bromide- Adverse reactions

Answer 5

Palpitations, dizziness, anxiety, headache, nervousness, dry mouth, nausea and vomiting.

Question 6

Ipratropium Bromide- dosage and administration

Answer 6

Adult: 500 mcg via small volume nebulizer (administered with a beta agonist), May repeat in 20 minutes up to three doses

Ped: 350 - 500 mcg (Rest is same as adult)

Question 7

Ipratropium Bromide- Duration of action

Answer 7

Onset: 15 mins
Peak effects: 1 hour
Duration: 4-6 hours

Question 8

Ipratropium Bromide- special considerations

Answer 8

Give in conjunction with a beta agonist, not the primary treatment for bronchospasms

Question 9

Ipratropium Bromide- pregnancy category

Answer 9

B

Question 10

Ipratropium Bromide- how supplied

Answer 10

500 mcg in 3 mL saline packs