substance abuse Flashcards
Impaired control over use
can’t quit, using over longer periods of time than intended
social impairment
affecting one’s relationships, work, school, including not engaging in activities in order to use the substance.
risky use
driving drunk, risky sex, using even though it’s making a medical condition worse
pharmalogical
tolerance and withdrawal
addictiveness of drugs
heroin
cocaine
tobacco
methadone
barbiturates
Alcohol
amphetamines
benzos
cannabis
ecstasy
LSD
Rated harm of drugs
most harmful: heroin, cocaine, barbiturates, street methadone, alcohol
Least harmful: Khat, Alkylnitrates. ecstasy, GHB, anabolic steroids
Gateway theory
Theory proposing that use of certain drugs of abuse, particularly during childhood or adolescence, increases the risk of progressing to other substances. For example, tobacco or alcohol have been proposed as gateways to marijuana use, and in turn marijuana has been proposed as a gateway to so-called “hard drugs” like cocaine or heroin.
ALDH2 & Gateway Theory
ALDH2 prevents alcohol use through a molecular pathway specific
to processing of alcohol
* If Gateway Theory is correct, these protected individuals should then
be at reduced risk for use of harder drugs