Structure of the cell Flashcards

1
Q

what is a eukaryote cell

A

cell that contains membrane bound organelles

- organelles are suspended in cytosol

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2
Q

what is evidence of cellular arrangement

A

light microscope x1500 allows cells to be seen clearly

- electron microscope x50000 can see the ultrastructure of cells - confirms proposed arrangement

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3
Q

What is the function of the cell membrane

A
  • separates the cytoplasm from the outside environment
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4
Q

structure of cell membrane

A

fluid mosaic model

  • phosphate head attached to a fatty acid chain
  • bilayer - tails point inwards
  • cholesterol molecules
  • lots of integral & peripheral proteins
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5
Q

what is the function of cholesterol in the CSM

A
  • help regulate fluidity and stiffens it
  • prevents small water soluble molecules from passing through
  • provides a suitable molecular environment for some transmembrane proteins
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6
Q

what is the function of integral & peripheral proteins in the CSM

A

integral-allow different substances in and out of cells

peripheral- can act as receptors

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7
Q

what is the structure of the nucleus

A

large double membrane-bound organelles that contains chromatin and the nucleolus
- nuclear envelope has pores and is selectively permeable between the nucleus and the cytoplasm

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8
Q

what does the nucleolus contain

A

DNA, RNA and proteins which regulate the cell cycle

- site for rRNA synthesis

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9
Q

what is the function of mitochondria?

A

generate chemical energy (ATP) necessary for biochemical reactions with aerobic stages respiration

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10
Q

what do number of mitochondria indicate?

A

level of metabolism

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11
Q

which cells have many mitochondria and why?

A

hepatocytes - active role in digestion
sperm cell - need ATP for motility
slow twitch skeletal muscle- high aerobic activity

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12
Q

structure of endoplasmic reticulum

A

3D network of cavities, some sac like and some tubular, bounded by membranes
- two types RER AND SER

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13
Q

structure and function of RER

A
  • surface studded by ribosomes which are essential for protein synthesis
  • packages and folds primary and secondary proteins into tertiary ones and transports in vesicles to golgi
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14
Q

which cells contain lots of RER

A

pancreatic epithelial - synthesis proteins to release into the lumen
plasma cells - to produce antibodies
nerve cell bodies - to produce proteins that are used internally and transported along the axon along microtubules

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15
Q

structure and function of SER

A

no ribosome on the surface
single tubular sacs
involved in lipid, glycogen and steroid synthesis and the detoxification of noxious substances

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16
Q

where is lots of SER found?

A

liver cells - lipid synth and detoxification of drugs by xenobiotic degradation

17
Q

structure of Golgi apparatus

A
  • stacks of parallel flattened membrane pockets (cisternae)
18
Q

function of golgi

A

modifies tertiary into quaternary or lipo/glycoproteins

  • dehydrates enzyme secretions
  • produce lysosomes
19
Q

lysosomes structure and functions

A

membrane bound organelles that contain hydrolytic enzymes

- decompose substances taken into the cell and destroy worn out organelles and foreign proteins

20
Q

what is glycogen

A

polymer of alpha glucose that is highly branched and absorbed from the digestive system and circulates in the blood
- can be made by most cells to allow ATP synth to take place

21
Q

why are lipid droplets found in some cells

A

store for triglycerides in the cytoplasm

22
Q

what is the structure of fat cells and why

A

nucleus pushed to the side
lack of organelles
capillaries in connective tissue between the cells
- this is because it is specialised for triglyceride storage

23
Q

what stain turns lipids black in an electron micrograph?

A

osmium

24
Q

what is the cytoskeleton

A

dynamic, 3D web like structure filling the cytoplasm that acts a framework to maintain the shape and polarity of the cell

25
Q

what are the components of the cytoskeleton

A

microfilaments
intermediate filaments
microtubules

26
Q

what are microfilaments

A

-strands of actin (contractile) so provide a dynamic framework

27
Q

where are microfilaments important

A

microvilli - act as a core through the projection to increases SA, allow motility and anchor is to the actin cortex of the cell

28
Q

what are intermediate filaments for?

A

purely structural and form assemblies inside the cell

there are 5 classes (e.g. neurofilaments)

29
Q

what are microtubules

A

largest component of cytoskeleton and made of subunits that can assemble/disassemble to provide for changes in cell shape and position of organelles

30
Q

what is the structure of centrioles

A

come in pairs

bundle of 9 tubules in star formation - one is vertical and one is flat

31
Q

what is the function of centrioles

A

maintaining cell shape in non dividing cells and tracts for transporting vesicle and organelles to move from place to place

  • responsible for polymerising microtubules
  • in a dividing cell centrioles replicate, separate and move to opposite sides of the cell to pull out the mitotic spindle and cause separation of the cell
32
Q

erythrocytes shape and reasoning

A

disc shaped cells
lack nucleus and organelles
can deform when passing through narrow channels and shape allows a lot of Hb

33
Q

nerve cell structure and reasoning

A

long axon as there is need to communicate to the periphery

34
Q

epithelial cell structure and reasoning

A

columnar cells and crushed together with high cell to cell contact - act as a barrier

35
Q

skeletal muscle cell structure and reasoning

A

long and thin
multinucleated
allow contraction to take place with sliding filament theory