structural protiens

Question 1

principal protein filaments in cytoskeleton

Answer 1

actin, microtubules, and intermediate filaments

Question 2

cytoskeleton

Answer 2

complex network of protein filaments, maintains cell shape and structure, whole-cell movement

Question 3

extracellular matrix

Answer 3

tissues contain materials deposited outside cells

Question 4

macromolecules of ECM

Answer 4

glycosaminoglycans and proteoglycans, fibrous proteins, adhesive proteins

Question 5

actin function

Answer 5

(1) regulation of the physical state of the cytoplasm,
(2) cell movement,
(3) formation of contractile rings in cell division

Question 6

regulators of gel-sol state of the cytoplasm

Answer 6

sequestering stop polymerization “sol”, cross-linnking F-actin “gel”, bundling of F-actin “gel”, fragmenting of F actins “gel” to “sol”

Question 7

actin function

Answer 7

(1) regulation of the physical state of the cytoplasm,
(2) cell movement,
(3) formation of contractile rings in cell division

Question 8

spectrin

Answer 8

actin binding maintains RBC biconcave shape

Question 9

dystrophin

Answer 9

actin binding protein that links actin to basal lamina and provides tensile strength to muscle

Question 10

Duchene MD

Answer 10

mutation in DMD gene that encodes dystrophin,

no functional dystrophin, rapid severe muscle degeneration

Question 11

Becker MD

Answer 11

mutation in DMD gene that encodes dystrophin;

partially functional dystrophin, slowly progressive muscle weakness