Stroke- pathology and investigation 1 Flashcards

1
Q

what is a stroke?

A

a neurological deficit ( loss of function) of sudden onset and lasting more than 24 hours. It is of vascular origin.

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2
Q

what is a transient ischaemic attack?

A

a neurological deficit of sudden onset and vascular origin that last less than 24hours

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3
Q

what are the symptoms of a stroke?

A
loss of power
loss of sensation
loss of speech (dysphasia)
loss of vision
loss of coordination
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4
Q

what is aphasia/ dysphasia?

A

language disorder marked by deficiency in the generation of speech

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5
Q

what must be found out during the history taking of a stroke?

A
time of onset
witnesses
headache
vomiting
neck stiffness
photophobia
loos of consciousness
fit 
incontinence
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6
Q

if a stroke patient has headache, vomiting, neck stiffness or photophobia what does this suggest?

A

haemorrhage

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7
Q

what are the findings on examination of a stroke patient?

A
motor function- clumsy or weak limbs
sensory function- loss of feeling
speech- dysarthria/ dysphasia
neglect/visuospatial problems
vsion-loss in one eye, or hemianopia
gaze palsy
ataxia
vertigo
incoordination
nystagmia
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8
Q

what is nystagmia?

A

condition in which the eyes make repetitive and uncontrolled movements, sign of stroke

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9
Q

what is ataxia?

A

neurological sign consisting of lack of voluntary coordination of muscle movements, sign of stroke

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10
Q

what is gaze palsy?

A

an inability to move both eyes in a single direction

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11
Q

what are the causes of strokes?

A
  • blood vessel occlusion by thrombus or embolus
  • haemorrhage
  • disease of vessel wall eg. atherosclerosis
  • disturbance of the normal properties of blood eg. thick blood from cancer
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12
Q

what is penumbra?

A

tissue that is alive but not perfused. It is at risk of infarction but can be saved if reperfused

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13
Q

what are the three circulations within the brain?

A

anterior circulation
posterior circulation
circle of WIllis

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14
Q

what is the Broca’s area of the brain responsible for?

A

speech

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15
Q

what is the frontal lobe responsible for?

A

judgement, foresight and voluntary movement

smell

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16
Q

what is the motor cortex of the brain responsible for?

A

movement

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17
Q

what is the sensory cortex of the brain responsible for?

A

heat, pain and other sensations

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18
Q

what is the parietal lobe responsible for ?

A

comprehension of language

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19
Q

what is the temporal lobe responsible for?

A
  • hearing

- intellectual and emotional functions

20
Q

what is the occipital lobe responsible for?

A

sight (primary visual area)

21
Q

what is the Wernicke’s area of the brain responsible for?

A

speech comprehension

22
Q

what is the cerebellum responsible for?

A

coordination

23
Q

what is the brainstem responsible for?

A
swallowing
breathing
heart beat
wakefullness centre
other involuntary functions
24
Q

if a stroke is small but affects deep white fibres what will the result be?

A

it will result in a large deficit as the fibres are packet close together here

25
what are the 5 causes of ischaemic stroke?
- large artery atherosclerosis - cardioembolic - small artery occlusion - cryptogenic - rare causes such as arterial dissection and venous sinus thrombosis
26
what are two kinds of haemorrhagic stroke?
``` primary intracerebral haemorrhage secondary haemorrhage (subarachnoid or atriovenous malformation) ```
27
what does the internal carotid artery supply?
the brain
28
what does the external carotid artery supply?
the face
29
what is the main problem caused by brain stem strokes?
inability to swallow
30
what is the most common cause of cardioembolic stroke?
atrial fibrillation
31
why is it important to localise stroke?
- confirms the diagnosis of a stroke - allows better selection of imaging - gives an indication of cause - gives an indication of prognosis
32
what is unilateral field loss?
loss of vision in one eye
33
what is bitemporal hemianopia?
loss of vision from one half of each, the loss is in the opposite halves
34
what is homonymous hamianopia?
loss of sight from one side in both eyes, the loss is from the same side in both eyes
35
what is a total anterior circulation stroke due to?
occlusion of proximal middle cerebral artery or internal carotid artery
36
what are the symptoms/signs of total anterior circulation stroke?
``` weakness sensory deficit Homonymous hemianopia (loss of vision) Higher cerebral dysfunction (eg dysphasia, dyspraxia) ```
37
what is dyspraxia?
the partial loss of the ability to co-ordinate and perform skilled, purposeful movements and gestures with normal accuracy. (apraxia is the total loss)
38
what is partial anterior circulation (PACS) caused by?
occlusion of branches of MCA
39
what are the symptoms of PACS?
``` 2/3 features TACS ie. weakness sensory deficit Homonymous hemianopia (loss of vision) Higher cerebral dysfunction (eg dysphasia, dyspraxia) ```
40
what is occluded in lacunar stroke (LACS)?
a lacunar artery
41
what are the symptoms of LACS?
either: -pure motor problem problem: Complete or incomplete weakness of 1 side, involving the whole of 2 of 3 body areas (face/arm/leg) -pure sensory Sensory symptoms and/or signs, same distribution -sensorimotor combination of above -ataxic hemiparesis often silent
42
what is ataxic hemiparesis?
paresis of contralateral leg and side of the face, ataxia of the contralateral leg and arm
43
which classification of stroke has the best prognosis?
LACs
44
which classification of stroke has the poorest prognosis?
TACs
45
which classification of stroke has the highest recurrence rate?
PACs