stress diathesis Flashcards
what is stress deiathesis
mental disorder and medical condition cause by genetic and enviromental
aestiology of diathesis stress-howes and mc cutcheon 17
microglia cells
- activation of cells response to stress
geentics and microgali
- important in central nervious system in protecting neurons and development of brain synaptic pruning
whats synamptic pruning
process brain develop from child to adult hood- helping refind brain neural circuits
abnormal microgali leads to sizo for two reasons
excessive pruning-damage PRE FRONTAL CORTEC AND HIPPOCAMPUS= cognetive and negative symptoms
dopamine system effect- positive symptoms
diatheisis explain more people vulnerable to abnormal micorglial function
events can effect mircogalial function as part of immune system
- pernantal flu
-childhood trauma
interactional approach
allows combination exmaining
biological
psychological
and social triggers
xie et al 18- used questionaire outpatients from psychiatrist in south china
- assesses child hood traum, social and suicidal
depression- 55 percent
schizo- 47