Stress Flashcards

1
Q

What controls stress?

A

Hypothalamus

  • Nervous system = sympathetic
  • Endocrine system
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2
Q

What is short term response to stress?

A

Sympathetic nervous system

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3
Q

What is Long term response to stress?

A

Endocrine system

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4
Q

What is the fight or flight short response?

A

Hypothalamus in CNS > Symp. > Adrenal gland > releases Adrenaline/Noradrenaline

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5
Q

What is central part of adrenal gland?

A

Adrenal Medulla

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6
Q

What does inner adrenal medulla give?

A

Brief response

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7
Q

What does outer adrenal cortex give?

A

Long lasting response

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8
Q

How is rapid response bought about?

A

granules stored with (nor)adrenaline

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9
Q

What does Adrenaline increase?

A

glycogenolysis- inc blood glc
gluconeogenesis - inc blood glc
mobilisation of free fatty acids

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10
Q

what does noradrenaline bind to in vasoconstriction

A

alpha 1 receptor

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11
Q

What does adrenaline bind to in vasodilation ?

A

Beta 2 receptor in skeletal muscle

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12
Q

how does adrenaline and noradrenaline increase blood glucose?

A

inhibit insulin and stimulate Glucagon

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13
Q

What is Phaechromocytoma?

A

benign tumour in adrenal medulla

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14
Q

What happens when adrenal cortex is stimulated?

A

Cortisol released

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15
Q

How is cortisol released?

A

Circadian rhythm - continually secreted

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16
Q

What hormones trigger Cortisol release?

A

Corticotropin- hypothalamus

Adrenocorticotropic hormone- anterior pituitary

17
Q

What are biological effects of cortisol?

A

Carb metabolism
Fat metabolism
Protein metabolism

18
Q

What does Carb metabolism do?

A

blood glucose increase, inc. gluconeogenesis

decrease glc utilisation

19
Q

What does fat metabolism do?

A

inc. fatty acis for energy use instead of Glc

20
Q

What are the effects of cortisol ?

A

increase BP- Vasoconstriction
increase HR
Anti inflammatory response - immune response decr. so no autoimmune disease

21
Q

What are the steps of Cortisol release?

A

1) stress stimulate Hypothalamus
2) CRH secreted and anterior then releases ACTH
3) ACTH stimulates adrenal cortex to release Cortisol
4) Neg feedback when too much cortisol

22
Q

What is Cushing Disease? ( Moon face/ buffalo hump)

A

Hypersecretion of cortisol

tumor in adrenal cortex and anterior pituitary gland

23
Q

What is Adison’s disease?

A

Hyposecretion of cortisol

Adrenal cortex and anterior pituitary damaged

24
Q

What is symptom of adisons disease?

A

Low BP

hypoglycaemia