Streptococcus Flashcards

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1
Q
  1. Are staphs catalase + or -?
  2. Are streps catalase + or -?
A
  1. Staphs are catalse +
  2. Streps are catalase -
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2
Q

What change in the RBCs contributes to alpha hemolysis?

A

RBCs are still present in the media but the hemoglobin has been changed to methemoglobin

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3
Q
  1. What are the groups used to group the streptococci?
  2. How are they grouped?
A
  1. Lancefield groups
  2. Cell wall carbohydrates
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4
Q

Streptococcus capsule:

Important with some streptococcual groups, especially ____ which have a capsule composed of ____ ____. This not only masks the organism but mimics ____ ____. Protects from ____.

A

Streptococcus capsule:

Important with some streptococcal groups, especially group A which have a capsule composed of hyaluronic acid. This not only masks the organism but mimics host tissues. Protects from phagocytosis.

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5
Q

List 5 toxins of Streptococcal species:

A
  1. Streptolysin-O
  2. Streptolysin-S
  3. Streptokinase
  4. DNase
  5. Hyaluronidase
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6
Q

What toxin is being described?

Leukotoxin

Attacks RBCs

Causes complete hemolysis

Toxic to platelets and fibroblasts

Very antigenic

A

Streptolysin-O

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7
Q

Which toxin is being described?

Less toxic

Non-antigenic

Produces the hemolysis that is usually seen

A

Streptolysin-S

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8
Q

Which toxin is being described?

In addition to lysing fibrin, this enzyme is able to cleave C3.

A

Streptokinase

(fibrinolysin)

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9
Q

All strains of Group A streptococci produce at least one ___ that assists in ____.

A

All strains of Group A streptococci produce at least one nuclease that assists in liquefaction of pus and obtaining nutrients.

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10
Q

Hyaluronidase breaks down ____ ____ in tissues and is considered to be a ____ ____.

A

Hyaluronidase breaks down hyaluronic acid in tissues and is considered to be a spreading factor.

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11
Q

Group A streptococcus is synonymous with what?

A

Strep pyogenes

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12
Q
  1. What is the natural habitat of strep pyogenes?
  2. True or False: most children have been infected with this organism by the time they are 10.
  3. True or False: different M-protein types tend to circulate through susceptible populations.
A
  1. Human pharyngeal and tonsillar areas
  2. TRUE
  3. TRUE
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13
Q

What is the major virulence facotr of Group A streptococci?

A

M-proteins

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14
Q

What does Group A strep cause in humans?

A

Strep throat

Scarlet fever

Sinusitis

Heart valve lesions

Glomerulonephritis

Rheumatic fever

Erysipelas

Necrotizing fasciitis

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15
Q

What toxins produce the rash and fever in scarlet fever?

A

Erythrogenic toxins

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16
Q

Which organism(s) is/are in lancefield group C?

A

Strep equi subspecies equi

Strep equi subspecies zooepidemicus

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17
Q

How is strep equi transmitted from horse to horse?

A

Fomite

Contact

Droplet

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18
Q

Where is Strep equis habitat?

A

Horse upper respiratory tract and reproductive tract

19
Q

From the respiratory tract, how does strep equi cause disease in a horse?

A

In the respiratory tract, the organism enters through the nasal epithelial cells and tonsils and travels via the lymph to the submandibular and other lymph nodes of the head and neck.

20
Q

Which virulence factor is part of strep equi and serves an antiphagocytic purpose?

A

M-protein

21
Q

Which is the most common cause of metritis in horses?

A

Strep zooepidemicus

22
Q

What has been responsible for recent outbreaks of hemorrhagic pneumonia is dogs?

A

Strep zooepidemicus

23
Q

What is the cause of “alpaca fever” in South America?

A

Strep zooepidemicus

24
Q

What is the natural habitat of strep zooepidemicus?

A

Skin

Upper respiratory mucosa

Tonsillar & phyarngyeal lymphoid tissues

25
Q

What is the most common cause of wound infections in horses?

A

Strep zooepidemicus

26
Q

What is the most common cause of uterine and cervical infections in mares?

A

Strep zooepidemicus

27
Q

What is associated with metritis and cervicitis in sows?

A

Strep equisimilis

28
Q

What else does Strep equisimilis cause?

A

Suppurative arthritis in pigs

Vegetative valvular endocarditis

Repro tract infections in dogs

29
Q

What makes up lancefield group G?

A

Strep canis

30
Q

Name 3 conditions strep canis causes in dogs.

(There are 5)

A
  1. Tonsilitis
  2. Metritis
  3. Umbilical infections
  4. Septicemia
  5. Wound infections
31
Q

What is the natural habitat of strep canis?

A

Male dog genital tract

32
Q

What is strep canis most likely to cause in cats?

A

Wound infections

33
Q

What makes up lancefield group E?

A

Strep porcinus

34
Q

What conditions does strep porcinus cause?

A

Jowl abscesses in pigs

Genitourinary infections in women

35
Q

What lancefield group is Strep suis?

A

Group D

36
Q

What are the 3 virulence factors for strep suis?

A

Muramidase released protein

Extracellular protein factor

Suilysin

37
Q

What is suilysin?

A

A cholesterol-binding hemolysin

38
Q

How does strep suis enter into the body of say a human being?

A

Cuts

Abrasions

Conjunctiva

39
Q

Which age of pig does strep suis affect?

A

Young pigs:

At birth OR shortly after

40
Q

What types of disease does strep suis cause in piglets?

A

Meningitis

Arthritis

Septicemia

Bronchopneumonia

41
Q

What diseases does strep suis cause in human beings?

A

Meningitis

Pneumonia

Arthritis

Endocarditis

Toxic shock syndrome

Hearing loss

42
Q

Which lancefield group is strep dysgalactiae in?

A

Group C

43
Q

Camp test for :

Strep agalactiae?

Strep dysgalactiae?

Strep uberis?

A

Strep agalactiae (+)

Strep dysgalactiae (-)

Strep uberis (15% +)