Bacillus anthracis produces a 3 component toxin that is highly lethal. 1. What are those 3 toxins? 2. What are their functions?

1. Protective antigen Binding unit 2. Edema factor Interferes with cell function by activating adenylate cyclase 3. Lethal factor Cleaves the kinase (MAPK/ERK) involved in signal transduction in CD4+ T-lymphocytes and fibroblasts Inhibits IL2 production

Gram + Rods Flashcards by Angela Bryan

Bacillus anthracis produces a 3 component toxin that is highly lethal.

What are those 3 toxins?
What are their functions?

Protective antigen
- Binding unit
Edema factor
- Interferes with cell function by activating adenylate cyclase
Lethal factor
- Cleaves the kinase (MAPK/ERK) involved in signal transduction in CD4+ T-lymphocytes and fibroblasts
- Inhibits IL2 production

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What is the Bacillus anthracis capsule composed of?

Poly-D-glutamic acid

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