Pasteurella Flashcards
What is the wommon habitat of Pasteurella multocida?
Common worldwide
Upper respiratory tract
Oral cavity (especially in dogs & cats)
Which subspecies of Pasteurella is the most common cause of fowl cholera?
Pasteurella multocida subspecies multocida
Besides Pasteurella multocida subspecies multocida, what are the other 2 subspecies?
Septica
Gallicida
What is Pasteurella’s appearance when stained with Giemsa or Wright’s stains?
Bipolar
True or False:
- Some fresh isolates of Pasteurella multocida are encapsulated.
- Capsule composition varies according the Type, but always consist of a polysaccharide.
- TRUE
- TRUE
What are the 2 typing systems for Pasteurella multocida?
Capsular typing
Somatic antigen typing
Capsular Type A is a component of ____ _____ ____ in cattle, along with which you may see ____ in the lungs.
Capsular Type A is a component of SHIPPING FEVER PNEUMONIA in cattle, along with which you may see ABSCESSES in the lungs.
True or False
Type A:5 is most commonly associated with the shipping fever pneumonia in cattle.
FALSE
Type A:3
Explain the immunization protocol of cattle for Pasteurella multocida TYPE A
Bacterins are rutinely used in preconditioning of feeder calves. Benefit is doutful, especially once animals are stressed. Must have 2 or more doses.
Modified live vaccines have so far proven too toxic or ineffective.
What polysaccharide makes up the capsule composition of P. mult Type A?
Hyaluronic acid
What are the 5 different capsular types for Pasteurella multocida?
A
B
D
E
F
How many somatic antigens are there for Pasteurella multocida?
16
True or False
- Type B has been isolated from bisoin in Yellowstone National Park and Canada.
- This disease could pose a threat to the cattle in the U.S.
- Type E has been isolated from animals in the U.S.
- TRUE
- FALSE - Does not appear to be a threat to cattle in the U.S.
- FALSE - Type E is only in Africa
What type of disease do Types B and E cause?
Hemorrhagic septicemia
Type A causes what disease in swine?
Pneumonia
Type D causes what disease in swine?
Atrophic rhinitis
Which virulence factor of Pasteurella multocida causes the atropic rhinitis in swine?
Cytotoxin
What are 3 systemic effects of the Type A cytotoxin?
- Depressed growth
- Hepatotoxicity
- Alteration of bone growth
In association with Pasteurella multocida, the cytotoxin is a single polypeptide that binds to host cell ganglioside receptors.
Once inside the host cell, the toxin activates what?
G protein
Causes an increase in osteoclastic activity and a decrease in osteoblastic activity
Type A is the cause of what 2 disease in sheep?
Pneumonia
Mastitis
Which Type(s) of Pasteurella multocida cause snuffles in rabbits?
Which is the most common cause?
Type A (most common)
Type D
What is perhaps the NUMBER 1 cause of economic loss to the poultry industry in the U.S.?
Pasteurella multocida TYPE A
Which subspecies are most commonly found in human infections?
Subspecies multocida
Subspecies septica
In what percentage of cat mouths is P. mult found?
90%
What is the Pasteurella species that affects lab animals, mice, guinea pigs, rats, and hamsters?
Pasteurella pneumotropica
What conditions or diseases can Pasteurella pneumotropica cause?
Abscessing pneumonia
Conjunctivitis
Subcutaneous abscesses
Mastitis
Name the following organism:
This organism is an occasional part of the normal fora of the mouth and intestinal tract of swine. It has been isolated from skin ulcers or bite wounds in Danish pig farmers.
Pasteurella aerogenes
Name the following organism:
This organism is isolated occasionally from respiratory and other infections in horses.
Pasteurella caballi
