STIs

Question 1

incubation time for primary syphilis

Answer 1

3 weeks

Question 2

incubation time for secondary syphilis

Answer 2

4-8 weeks after primary

Question 3

incubation for tertiary syphilis

Answer 3

1-30 years

Question 4

incubation for N. gonorrhoeae

Answer 4

2-6 for acute symptoms, days-weeks for disseminated

Question 5

incubation for Clamydia

Answer 5

7-21 days

Question 6

incubation for HPV

Answer 6

highly variable but usually 2-20 months

Question 7

why would you culture in high CO2

Answer 7

older method to detect N. gonorrhoeae

Question 8

how do you detect HPV

Answer 8

PCR

Question 9

how do you detect N. gonorrhoeae and chlamydia?

Answer 9

urethral DNA probe

Question 10

how do you Dx syphilis

Answer 10

RPR (rapid plasma reagin) or VDRL screen for Abs
false positives with other conditions so must be confirmed with FTA
primary syphilis can also be Dx with dark field microscopy, but not always avaialable

Question 11

conditions which can cause false post RPR

Answer 11

SLE
mono
malaria
leprosy
hep A
HIV
pregnancy

Question 12

gram stain

Answer 12

could ID N. gonorrhoeae as gram neg intracellular coffee-bean shaped diplococci

Question 13

what is the lesion of primary syphilis

Answer 13

chancre- painless

Question 14

chancroid

Answer 14

caused by H. ducreyi
painful
unilateral lymphadenopathy common
usually associated with sex trafficking or drug users

Question 15

Tx for syphilis

Answer 15

IM Bicillin

one dose if yr

Question 16

what organism causes syphilis

Answer 16

Treponema pallidum

spirochete

Question 17

what is the lesion of HPV called

Answer 17

condyloma acuminata

Question 18

how does HIV present

Answer 18

nonspecific viral syndrome with fever, sore throat, swollen lymph nodes, and transient maculopapular rash

Question 19

Chlamydia trachomatis presentation

Answer 19

can first present with PID
lower abdominal pain
urinary frequency/dysuria
Fitz-hugh-curtis syndrome
cervicitis 
can cause lymphogranuloma venereum

Question 20

Tx Chlamydia

Answer 20

obligate intracellular therefore penicillins and cephaloporins not effective
use macrolides (azithromycin) or tetracyclines 
and Tx for gonorrhea

Question 21

Tx gonorrhea

Answer 21

ceftriaxone only option

Question 22

Tx for trichomonas vaginalis

Answer 22

metronidazole

tinidazole

Question 23

herpes simplex 2

Answer 23

painful cluster of vesicles which burst -> ulcers

incubation 4-7 days

Question 24

Klebsiella granulomatous

Answer 24

causes granuloma inguinale
rare in US
can cause autoamputation

Question 25

how do you Dx H. ducreyi

Answer 25

culture in chocolate agar

Question 26

how do you Tx H. ducreyi

Answer 26

ceftriaxone
azithromycin
single dose of either

Question 27

kelbsiella granulomatous Dx

Answer 27

Bx

Question 28

kelbsiella granulomatous Tx

Answer 28

erythromycin or tetracyclin for 3 weeks

ampicillin for 12 weeks

Question 29

Dx herpes simplex-2

Answer 29

viral culutres PCR

Tzanck smear

Question 30

Tx of herpes simplex-2

Answer 30

acyclovir
famciclovir
valacyclovir

Question 31

N. gonorrhoeae

Answer 31

PID
migratory polyarthritis
sparsely distributed necrotic pustules

Question 32

genital ulcers

Answer 32

syphilis- painless
herpes- painful
chancroid- painful
lymphogranuloma venerum

Question 33

urethritis and cervicitis

Answer 33

N. gonorrhoeae

Chlamydia

Question 34

genital warts

Answer 34

HPV

secondary syphilis