STIs Flashcards
incubation time for primary syphilis
3 weeks
incubation time for secondary syphilis
4-8 weeks after primary
incubation for tertiary syphilis
1-30 years
incubation for N. gonorrhoeae
2-6 for acute symptoms, days-weeks for disseminated
incubation for Clamydia
7-21 days
incubation for HPV
highly variable but usually 2-20 months
why would you culture in high CO2
older method to detect N. gonorrhoeae
how do you detect HPV
PCR
how do you detect N. gonorrhoeae and chlamydia?
urethral DNA probe
how do you Dx syphilis
RPR (rapid plasma reagin) or VDRL screen for Abs
false positives with other conditions so must be confirmed with FTA
primary syphilis can also be Dx with dark field microscopy, but not always avaialable
conditions which can cause false post RPR
SLE mono malaria leprosy hep A HIV pregnancy
gram stain
could ID N. gonorrhoeae as gram neg intracellular coffee-bean shaped diplococci
what is the lesion of primary syphilis
chancre- painless
chancroid
caused by H. ducreyi
painful
unilateral lymphadenopathy common
usually associated with sex trafficking or drug users
Tx for syphilis
IM Bicillin
one dose if yr
what organism causes syphilis
Treponema pallidum
spirochete
what is the lesion of HPV called
condyloma acuminata
how does HIV present
nonspecific viral syndrome with fever, sore throat, swollen lymph nodes, and transient maculopapular rash
Chlamydia trachomatis presentation
can first present with PID lower abdominal pain urinary frequency/dysuria Fitz-hugh-curtis syndrome cervicitis can cause lymphogranuloma venereum
Tx Chlamydia
obligate intracellular therefore penicillins and cephaloporins not effective use macrolides (azithromycin) or tetracyclines and Tx for gonorrhea
Tx gonorrhea
ceftriaxone only option
Tx for trichomonas vaginalis
metronidazole
tinidazole
herpes simplex 2
painful cluster of vesicles which burst -> ulcers
incubation 4-7 days
Klebsiella granulomatous
causes granuloma inguinale
rare in US
can cause autoamputation
how do you Dx H. ducreyi
culture in chocolate agar
how do you Tx H. ducreyi
ceftriaxone
azithromycin
single dose of either
kelbsiella granulomatous Dx
Bx
kelbsiella granulomatous Tx
erythromycin or tetracyclin for 3 weeks
ampicillin for 12 weeks
Dx herpes simplex-2
viral culutres PCR
Tzanck smear
Tx of herpes simplex-2
acyclovir
famciclovir
valacyclovir
N. gonorrhoeae
PID
migratory polyarthritis
sparsely distributed necrotic pustules
genital ulcers
syphilis- painless
herpes- painful
chancroid- painful
lymphogranuloma venerum
urethritis and cervicitis
N. gonorrhoeae
Chlamydia
genital warts
HPV
secondary syphilis
