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Hugh's MD1 Reproduction > STI's > Flashcards

STI's Flashcards

1
Q

What is Fitz-Hugh-Curtis Syndrome?

A

Peri-hepatitis due to an ascending gonorrhoea infection that causes inflammation in the hepatic capsule

Characterised by violin-string adhesions in the capsule

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1
Q

What is used to diagnose Trichomonas vaginalis?

A

Wet prep of vaginal swab

PCR on urine if available

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1
Q

What is the most common method of diagnosis for syphilis?

A

Serology

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2
Q

How does the discharge in Gonorrhoea appear?

A

Thick, creamy

Can clog the urethra

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3
Q

What is the most common SIT?

A

Chlamydia

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3
Q

What is the trichomonas treated with?

A

Metronidazole 2g orally, single use

Tinidazole 2g orally, single use if metronidazole isn’t well tolerated

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4
Q

How do chlamydia bacteria appear histologically?

A

They are obligate intracellular pathogens

Characteristic elementary bodies form

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6
Q

What is the incubation period for gonorrhoea?

A

2-7 days

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7
Q

Why is it important to distinguish neonatal gonococcal ophthalmia from other causes of conjunctivitis?

A

Because it requires IV antibiotics as apposed to topical antibiotics

  • Cefotaxime 50mg/kg IV, 8 hours, 7 days
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7
Q

Which cells does chlamydia infect?

A

Columnar epithelium

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9
Q

Are asymptomatic gonorrhoea infections more common in males or females?

A

Females (80% of infections are asymptomatic)

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10
Q

What samples are taken for gonorrhoea diagnosis?

A

Urine

Urethral swabs

Cervical swabs

Of samples from other areas the gonorrhoea can infect

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10
Q

How is Mycoplasma genitalium treated?

A

Azithromycin 1g

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11
Q

What is the causative agent of syphilis?

A

Treponema pallidum

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12
Q

What are common presenting signs of STI’s?

A

Vaginal or urethral discharge

Genital lesions

Warts - anus and genitals

Generalised dermatological signs

Pelvic involvement

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13
Q

What are some clinical signs of Trichomonas vaginalis?

A

Stawberry cervix (cervical erythema)

Frothy green-yellow vaginal discharge

Dysuria

Abdominal pain

Pruritis

14
Q

How is chlamydia treated?

A

Azithromycin 1g oral, 2 doses 1 week apart

or

Doxycycline, 100mg oral, BD

16
Q

What are the current, preferred treatment options for gonorrhoea?

A

Ceftriaxone 500mg IV/IM

Azithromycin 1g Oral

17
Q

What are the symptoms of chlamydia in males?

A

Dysuria

Meatal erythema (redness around the tip)

Clear urethral discharge

Testicular pain

Prostatitis

18
Q

Which stage of the chlamydia life cycle is infectious?

A

The elementary bodies

19
Q

What is the transmission rate of chlamydia to newborns?

A

50%

21
Q

For which infection is it common to test to see whether treatment has cured the disease?

A

Chlamydia

22
Q

Which STI’s can cause Pelvic Inflammatory Disease (PID)?

A

Gonorrhoea

Chlamydia

23
Q

What is clinical presentation of lymphogranuloma venereum?

A

It is a complication of chlamydia

Starts with a ulcerative genital lesion > Suppurative inguinal lymphadenopathy and procto-colitis (inflammation around rectum and colon)

24
Q

When do you test for cure with chlamydia infection?

A

4-6 weeks

and also after 3 months is advised

26
Q

What is the causative agent of chlamydia?

A

Chlamydia trachomatis

27
Q

What is the most common presentation of chlamydia in newborns?

A

Conjunctivitis

27
Q

What are some risk factors for Trichomonas vaginalis?

A

Risky sexual behaviour

Non steady partner

Marijuana use

29
Q

What disease does Mycoplasma genitalium cause?

A

Urethritis in males

Cervicitis, acute endometritis, PID in females

May persist for 3-6 months

30
Q

What is the clinical course of syphilis infection?

A

Primary infection: ulcer on genitals, 2-3 week post infection

Secondary infection: Generalised rash that will clear if left untreated

Early and late latent syphilis: Asymptomatic

Tertiary: 10-20 years later, can appear in any organ

Hugh's MD1 Reproduction (18 decks)

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