Intrauterine Programming of Adult Disease Flashcards
What is a possible complication of polyhydramnios (excess amnionic fluid)?
Preterm labour
How common is mild pre-eclampsia?
5-10% of births
What are the three hormones that drive fetal growth?
IGFs
Thyroid hormones
Insulin
How much does genotype account for birth size?
15%
How does the cause of fetal growth restriction differ in the Western society cf to the developing world?
Placental insufficiency
vs
Maternal undernutrition
When is accelerated growth after small birth weight a good thing?
When it returns the baby to the normal trajectory
What is a preterm labour defined as?
Labour before 37 weeks gestation
What is a breech in the context of pregnancy?
When the foetus comes out of the mother feet first
On average, how much bigger are male babies cf to females babies?
2%
What is pre-eclampsia characterised by?
High maternal blood pressure
Proteinuria
Placental dysfunction & intrauterine growth restriction
What causes intrauterine growth restriction?
Placental insufficiency
How is intrauterine growth restriction defined?
Low birth weight
or
Small-for-gestational age (IUGR)
What is the problem with being underweight?
Increased risk of developing adult disease
How is pre-eclampsia treated?
Immediate delivery
What percentage of deliveries are preterm?
5-8%
