Steven Johnson's Syndrome Flashcards

1
Q

What is Steven Johnson’s syndrome?

A

-potentially fatal acute skin disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how is Steven Johnson’s syndrome characterized?

A

widespread erythema and macule formation resulting in epidermal detachment or sloughing and erosion formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Steven Johnson’s syndrome mortality rate

A

1-5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what can trigger Steven Johnson’s syndrome?

A

medication reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what medications trigger Steven Johnson’s syndrome?

A

sulfonamides, anticonvulsants, NSAIDs, allopurinol, oxicam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Steven Johnson’s syndrome risk factors

A

-medications
-weakened immune system (Cancer & HIV)
-history of SJS
-family history of SJS
-genetic factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Steven Johnson’s syndrome clinical manifestations

A

Initially:
-burning or itching
-tenderness
-flu-like symptoms (fever, cough, sore throat, headache, severe malaise, aches/pains)

Followed by:
-rapid onset of erythema involving much of the skin surface and mucous membranes

-Large bull develop or large sheets of epidermis are shed

-excruciatingly tender, loss of skin leaves a weepings surface like a total body partial thickness burn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Steven Johnson’s syndrome Complications

A

-keratoconjunctivitis (inflammation of cornea and conductive) - impairs vision, scarring, corneal lesions
-dehydration
-respiratory failure
-sepsis
-MODS
-permanent skin damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Steven Johnson’s syndrome Management

A

-control of fluid and electrolyte balance
-prevention of sepsis and ophthalmic complications
-transfer to burn center
-medications: IVIG (IV immunoglobulin - blood product prepared from serum), cyclosporin, cyclophosphamide
-wound care

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Steven Johnson’s syndrome nursing interventions

A

-maintain skin & mucous membrane integrity
-attain fluid balance
-preventing hypothermia
-relieve pain
-reducing anxiety
-monitor and manage potential complications
-education

How well did you know this?
1
Not at all
2
3
4
5
Perfectly