Cushing's Disease/Syndrome Flashcards

1
Q

what is Cushing’s Disease?

A

excessive adrenocortical activity or corticosteroid medications

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2
Q

what is Cushing’s Disease the result of

A

a tumor in the pituitary gland, resulting in excessive release of ACTH

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3
Q

what is Cushing’s syndrome a result of

A

long-term use of glucocorticoids

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4
Q

Cushing’s syndrome clinical manifestations

A

-hypertension
-buffalo hump
-hyperglycemia
-hypokalemia
-moon face
-sodium retention
-impaired wound healing
-increased susceptibility to infections
-osteoporosis
-spontaneous fracture

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5
Q

diagnostics

A

-serum cortisol
-urinary cortisol (24 hr urine)
-low-dose dexamethasone suppression test
-CT & MRI

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6
Q

treatment

A

-hypophysectomy
-adrenalectomy

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7
Q

things to watch out for after surgery

A

-adrenal insufficiency symptoms may appear within 12-24 hours post op
-hypotension, fever, N/V, pallor, headache, abdominal pain, diarrhea

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8
Q

what are people with Cushing’s disease at an increased risk for?

A

-infection
-gastric ulcers
-bone fractures

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