Pancreatitis Flashcards
what is pancreatitis?
inflammation of the pancrease that ranges from mild to life-threatening
autodegestion
pancreatic enzymes destroy its own tissue
what sex is pancreatitis more common in?
males
why do males usually get pancreatitis?
alcoholism
acute pancreatitis pathology
-enzymes normally excrete in the duodenum are activated and in the pancreas or its ducts and start to auto digest pancreatic tissue
-consequent inflammation causes intense pain, 3rd spacing of fluid, pancreatic fat necrosis, & occasionally hemorrhage
chronic pancreatitis pathology
-progressive inflammatory changes lead to permanent structural damage
-exocrine and endocrine functions of the pancreas are disrupted
common causes of acute pancreatitis
-gallstones
-alcohol abuse
-hypertriglyceridemia
-genetic mutations
-drugs (antibiotics/antivirals)
-trauma to abdomen
-obstruction
-hypercalcemia
-infections
-idiopathic
-ERCP
common causes of chronic pancreatitis
-usually combination of factors
-genetic mutations
-idiopathic
acute pancreatitis risk factors
-smoking
-obesity
-biliary cysts
-abnormal organ obstruction
-family history of pancreatitis or pancreatic cancer
chronic pancreatitis risk factors
-alcohol abuse
-smoking
-recurrent acute pancreatitis
-ductal obstruction
-systemic disease (Lupus)
-obesity
complications of pancreatitis
-DM
-massive hemorrhage
-shock
-coma
-ARDS
-atelectasis or pleural effusion
-pneumonia
-paralytic ileus
-pancreatic abscess and cancer
-GI bleeding and obstruction
-chronic pancreatitis
-malnutrition
-pseudocysts
-acute kidney injury
-death
assessment of pancreatitis - history
-nausea
-vomiting
-predisposing factors
-history of alcohol or medication use
-myalgia & arthralgia
assessment of acute pancreatitis
-sudden, steady intense epigastric pain
-pain aggravated by consuming fatty foods or alcohol, walking or lying down, relieved by sitting up
-bloating
-diarrhea
assessment - physical findings
-hypotension
-tachycardia
-dyspnea or orthopnea
-basilar crackles
-pale complexion, diaphoresis, and listlessness (severe cases)
-confusion
-pleural effusion
-generalized jaundice
-hypoactive bowel sounds
-Cullen sign
-turner sign
-abnormal tenderness, distention, rigidity, and guarding
assessment of chronic pancreatitis
-intermittent or constant dull, to severe pain in mid to upper left abdomen, possibly radiating to back lasting for several hours
-pain aggravated by consuming fatty foods or alcohol
-weight loss
-steatorrhea