stem cells Flashcards
an early stage embryo is a ball of cells made up of…
stem cells
fertilisation is when…
a sperm cell joins with an ovum(egg cell)
when the ovum is fertilised, what process does it go through to form the embryo?
the fertilised ovum undergoes mitosis and forms a ball of cells called an embryo
what happens when the cells in an embryo become specialised?
they begin to form other specialised cells such as nerve cells and muscle cells
what is the process where cells begin to specialise called?
cell differentiation
over time, what do all of these cells come to form?
the adult organism
are cells in an early embryo differentiated or not?
no they have not differentiated. Any cell is capable of differentiating into any type of body cell
what is the definition of a stem cell?
a stem cell is an undifferentiated cell which can give rise to more cells of the same type and can differentiate to form other types of cells
where else can we find stem cells besides an embryo?
they can be found in adult organisms such as the bone marrow.
unlike embryonic stem cells, what can’t adult stem cells do?
unlike embryonic stem cells, adult stem cells can not differentiate into any other type of cell
why can’t stem cells in bone marrow differentiate to any type of cell?
because stem cells found in bone marrow are adult stem cells, they can only differentiate to limited specialised cells such as cells found in our blood
how are stem cells useful in medicine? (bone marrow)
•Bone marrow transplants - leukaemia is a cancer of the bone marrow,
to treat this,
first the patients existing bone marrow is destroyed using radiation
the patient then receives a transplant of bone marrow from a donor
the stem cells in the bone marrow now divide and form new bone marrow. They also differentiate and form blood cells
what’s a problem when transferring stem cells in a bone marrow transplant?
- the donor has to be compatible with the patient. Otherwise the white blood cells produced by the donated bone marrow could attack the patients body
- There is a risk that viruses can be passed from the donor to the patient
how can stem cells be useful in medicine? (therapeutic cloning)
- In therapeutic cloning, an embryo is produced with the same genes as the patient.
- which means that stem cells from the embryo can be transplanted into the patient without being rejected by the patients immune system.
- once inside the patient, the stem cells can then differentiate to replace cells which have stopped working correctly
what can therapeutic cloning be used for?
This technique can be used for a range of medical conditions such as diabetes or paralysis.