STD's in Tropics

Question 1

1/3 of HIV cases can be ascribed to what condition?

Answer 1

HSV2 infection

Question 2

What are characteristics of Chancroid infection?

Answer 2

PAINFUL chancre with induration

Question 3

What is the treatment of Chancroid?

Answer 3

Azithromycin 1gm po
Ceftriaxone 250 mg IM
Cipro 500 mg po bid for 3 days
Emycin base 500 mg po tid for 5 days

Question 4

What are characteristics of HSV infection?

Answer 4

Multiple, painful ulcers which are recurrent with tender inguinal nodes. The first episode may have flu like sx.

Question 5

What is the treatment of HSV

Answer 5

Acyclovir
Valcyclovir
Famvir
Initial episode treated for 7 to 10 days, recurrences are treated for 5 days

Question 6

What are the stages of Syphilis?

Answer 6

Primary
Secondary
Tertiary
Latent- absence of physical findings
Early Latent- infection occurred less than 1 yr
Late Latent- Infection occurred more than 1 year ago

Question 7

What tests are available to diagnose Syphilis?

Answer 7

Non-treponemal (VDRL/RPR)-correlates wit disease activity

Treponemal- FTA-ABS, TP-PA, EIA

Question 8

What is the treatment of Syphilis?

Answer 8

PCN, Ceftriaxone, Azithromycin, Doxycycline
PCN treatment: 2,4 million units IM X1 for primary, secondary and early latent
Late Latent is treated with the same amount of IM PCN 1x/week for 3 weeks
Neurosyphilis is treated with 20 to 24 million units per day IV for 10 to 14 days

Question 9

How does granuloma inguinale present?

Answer 9

A painless papule that progresses to a beefy ulcer with rolled edges with associated enlarged inguinal lymph nodes and fibrosis (Pseudobuboes)

Question 10

What is the treatment for Granuloma Inguinale?

Answer 10

All regimens are three weeks long:
Zithromax 1 gm weekly
Cipro 750 mg bid
Emycin 500 mg qid

Question 11

What causes Lymphogranuloma Venerum?

Answer 11

Chlamydia Trachomatus

Question 12

What are the clinical findings?

Answer 12

Herpetiform ulcers with enlarged tender, fluctuant inguinale buboes. It can present like inflammatory bowel disease in Men who have Sex with Men. It can also cause proctitis and rectal strictures.

Question 13

What HPV types cause cancer?

Answer 13

Types 6 and 18 give rise to 95% of Cervical Cancer

Question 14

To whom is the vaccine given and how long is it effective?

Answer 14

It is given to girls ages 9 to 13 years. Its effect lasts for 5 years.

Question 15

How effective is male circumcision?

Answer 15

HIV is reduced by 50%

It provides partial protection from genital ulcer diseases and viral infections. It does not protect against urethritis.