Non Typhoid Bacterial Diarrheas

Question 1

What are some facts to know about Campbylobacter Infection?

Answer 1

Some may have no sx
Usually in kids, resolves in 2 weeks
Causes 95% of travelers diarrhea
Results from ingestion of animal products
Causes a non inflammatory diarrhea in developing countries
Can be associated with bacteremia, meningitis, reactive or purulent arthritis
Guillan Barre Syndrome
Macrolides are the drugs of choice.

Question 2

What are some facts about non Typhoid Salmonella infections?

Answer 2

Illness lasts 3 to 7 days
Temp as high as 103 degrees for 3 days
Contracted from food animals
usually in the summer
increased in those with HIV
use 3rd generation Cephalosporins or FQ for enteric fevers

Question 3

What are the types of Shigella?

Answer 3

S. Dysenteriae
S. Flexneri
S. Boydii
S. Sonnei

Question 4

What is Shigella associated with?

Answer 4

Poverty

Question 5

How does Shigellosis present?

Answer 5

Frequent, small volume bloody mucoid stools.
Hemolytic Uremic Syndrome- occurs days 1 thru 5 post diarrhea labs show low Hgb and platelets with high bun and Creatinine

Question 6

How is Shigellosis treated?

Answer 6

in the 3rd World, start Nalidixic Acid ASAP. Other treatment include FQ, Zithromax and 3rd Generation Cephalosporins. Drug of choice in USA is TMP/SMX

Question 7

How many types of Diarrheogenic E Coli are there?

Answer 7

7-
ETEC-leading cause of travelers diarrhea
EHEC
EPEC
EAggEC- cause of malnutrition
EIEC
DAEC
EColi0157- starts as non bloody diarrhea followed by blood and cramping pain with vomiting and fever