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Biology
The study of living things, which we call organisms
Proteins (2)
- large, complex molecules made up of amino acids
- essential for the body to function properly
Prokaryotes
a single-celled organism that has no membrane bound organelles
Prokaryotes Tree
Prokaryotes
Bacteria archaea
(eukaryotes are larger cells that has a mitochondria)
Cellular Specialization
the process by which cells develop unique structures and functions to perform specific tasks within an organism
aerobic metabolism
The use of Di-Oxygen to extract energy
anaerobic metabolism
Gaining energy by extracting it from other living organisms
Genome
the complete set of DNA, or genetic material, in an organism
Genome tree
Genome - DNA(Genes) - Nucleotides
phylogenetic tree
a visual representation of the evolutionary relationships between organisms
genus
a taxonomic group covering more than one species
Has multiple species in this category
binomial
a two-term naming system that gives each species a unique scientific name
internal environment
the environment in which cells are found
homeostasis
keeping a stable internal enviorment in order to survive
controlled experiment
An experiment where a variable is manipulated (independent), and a variable is studied (dependent)
comparative experiment
a simple comparison of unmanipulated data
null hypothesis
the proposition that there is no effect or no relationship between phenomena or populations OR DATA
hydrogen bond
an electrostatic attraction between a hydrogen atom and another electronegative atom, such as nitrogen, oxygen, or fluorine
hydrophilic
Polar and therefore loves water
hydrophobic
non-polar and is water repellent
When does a chemical reaction occur?
When moving atoms collide with sufficient energy to combine or to change their bonding partners
Energy
capacity to do work
cohesion
the property of molecules of the same substance to stick together due to an attraction between them
acid
H+ donater
base
H+ acceptor
buffer
the maintenance of internal constancy-homeostasis. A mixture of a weak acid and its corresponding base, capturing the H+
Definition of a Macromolecule
Polymers that exceed molecular weight of 1000
Macromolecule Basic Structure
Polymer - Monomer
(Except Lipids)
4 Marcomolecules and explain simply
- Protein - 20 amino acids
- Carbohydrates - forms giant molecules by linking chemically
- Nucleic Acid - four kinds of nucleotide monomers linked
- Lipids - Forms large structures through nonpolar covalent bonds
Isomers
Same chemical formula, different arrangement
What are the three different types of Isomers?
- Structural isomers - complete re-arrangement
- Cis-Trans - Carbon Double Bond removed
- Optical - mirror image
Primary structure
(protein)
the linear sequence of amino acids in its polypeptide chain
Secondary Structure
(alpha) helix - coil of hydrogen bonds
(beta) pleated sheet - pleated hydrogen bonds
Tertiary Structure
3D bonded of secondary structure formed by hydrogen bonds - if these bond, it is called a quaternary structure
Carbohydrates
What is the formula and its role
(CnH2nOn) polymers that make up the larger part of the organism
Four types of Carbohydrates
- Monosaccharides - 1 cell sugars, simple sugars
- Disaccharides - 2 monosaccharides covalently linked
- Oligosaccharides - 3-20
- Polysaccharides - 20+
Glycosidic linkages
The Covalent bonding of monosaccharides that happens by condensation reactions
glucose
blood sugar (monosaccharide)
glycogen
water soluble glucose that is used to store glucose in liver and muscles and is used to store energy
Cellulose
a complex carbohydrate that is the chief part of the cell walls of plants
(It is strong because it is linear)
What are Lipids made of?
What is its characteristics?
Is made of non polar covalent bonds (Van Der Waals) which are hydrophobic
Triglycerides
Simple lipids
room temp solids- fats
room temp liquids - oils
How are Triglycerides made?
They are made by the ester linkage of glycerol (a small molecule with three -OH groups) and a fatty acid (nonpolar hydrocarbon chain) which releases water molecules
What is a saturated fatty acid, and what are its attributes?
Definition: All hydrocarbon chains are single bonds
Attributes: No Kinks, packed, high melting points, solids at room temperature
What is a unsaturated fatty acid, and what are its attributes?
Definition: All hydrocarbon chains are double bonds
Attributes: Kinks, poorly packed, low melting points, liquids at room temperature
amphipathic
both hydrophobic and hydrophilic
phospholipids
A lipid (fat) that contains phosphorus
What is the role of Nucleic Acids
polymers specialized for storage and transmittion.
DNA
Acid used for hereditary information
RNA
Acid used for protein information
Nucleotide
(Monomer of Nucleic Acid)
Sugar + Phosphate + Base
Nuceluoside
Sugar + Base
Pyrimidine
1 Ring Base of a Nucleic Acid
Purine
2 ring base of a nucleic acid
DNA Bases
- Adenine
- Cytosine
- Guanine
- Thymine
complementary base pairing: A-T, C-G
RNA bases
- Adenine
- Cytosine
- Guanine
- Uracil
complementary base pairing: A-U, C-G
DNA Replication
Exact DNA Replication
DNA Gene Expression
- RNA copies DNA - transcription
- RNA gives info to protein - translation
Genes
The sequence of DNA that are templates for protein
Spontaneous Generation
the supposed production of living organisms from nonliving matter
enzymes
- bind a substrate
- carry out chemical reactions
- release a product
- repeat
ribozymes
RNA enzymes
cells
the smallest unit that can live on its own and that makes up all living organisms and the tissues of the body
membrane
the outer barrier of nonbiological enviroment
protocells
circular fatty acids (theory)
How are the features in a eukaryotic cell compartmentalized?
- Each Organelle has a specific role.
- These roles are determined by the chemical reactions that happen within the organelle.
- Animal and plant cells carry both similarities and differences.
Ribosomes in Eukaryotic Cells vs Prokaryotic Cells
Eukaryotic - Found in specific areas
Prokaryotic -Free to roam
How are features of cells anaylzed? (2)
- Microscopy
- Cell Fragmentation - Plasma membrane is destroyed so that the contents flow out and are studied
Nucleus
(Largest Organelle)
Purpose
1. Location of DNA + DNA replication
2. Transcriptions - on or off
3. Region in nucleus, known as nucleolus, is where ribosomes are assembled.
Membrane - Nuclear Envelope
Endomembrane System
(Takes up a lot of volume)
Interconnected system of membrane that is flattened into sheets
Endoplasmic Reticulum (ER)
(system in cytoplasm)
This is composed of RER and SER
The Interior compartment is known as lumen
Rough Endoplasmic Reticulum (RER)
(actively involve with synthesis of protein)
1. RER receives into its lumen newly made protein away from cytoplasm
2. RER “tags” the protein to their location.
3. Proteins are then shipped to their location
4. Most membrane bound proteins are produced in ribosomes of RER and are sent to lumen.
Smooth Endoplasmic Reticulum (SER)
(No Ribosomes, proteins synthesized in RER are chemically modified lumen of SER)
1. It makes toxic cells more polar - making them soluble and removable
2. Glycogen degradation of animal cells
3. Lipids and Steroids
4. Stores Calcium Ions
Golgi Apparatus
(type of endomembrane system)
- It receives protein sacs from the RER
- It modifies, concentrates, and packages before sent to destination
- It modifies and attaches carbohydrates to proteins.
- The polysaccharides which will be sent to cell wall are synthesized.
Mitochondria
Purpose:
Harvests Chemical Energy (like ATP)
Explain the Mitochondria
1st membrane = smooth
2nd membrane = It has the control over what goes in and out
The second membrane has a wiggly shape.
gap = cristae
no gap = matrix
The matrix contains
1. enzymes
2. ribosomes
3. DNA
Lysosmes
(Part of Golgi Apparatus)
Purpose:
To degrade material taken up from outside the cell to digest obsolete comments
Chloroplasts
Purpose:
1. It uses photosynthesis to convert light to energy
2. It contains ribosomes and DNA
3. It stores red, yellow, and orange pigments
Membrane:
The membrane is a potato sack that has stacks.
Each stack is called granum, and each individual plate is known as grana
Other Membrane Enclosed Organelles
- Peroxisomes
- Glyoxysomes
- Vacuoles
Peroxisomes
Purpose:
accumulates toxic peroxides and breaks them down safely
Glyoxysomes
(in plants)
Purpose:
Lipids are converted into carbohydrates for transporting growing cells.
Vacuoles
Purpose:
1. Storage - Toxic Waste
2. Structure - it holds 90% of volume-plants
3. Reproduction
4. Digestion
What are the types of Cytoskeletons?
- Microfilaments
- Intermediate filaments
- Microtubes
Microfilaments
Purpose:
1. It allows entire cell parts to move
2. It determines and stabilizes cell shape
Intermediate Filaments
(Replaceable like fingernail or hair)
1. helps anchor cells
2. Resist Tension
Microtubes
Purpose:
1. It holds the rigid skeleton
2. It is the framework along which motor protein can move structures within the cell.