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Bacteriology > Staphylococci > Flashcards

Staphylococci Flashcards

1
Q

Staphylococci

  • gram?
  • shape?
  • live in high salt concentration
A
  • gram POSITIVE
  • coccus shape
  • HALODURIC
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2
Q 
Coagulase Test (2)
- what does clumping factor bind to?
A

Slide Test
Tube Test
- binds to fibrinogen

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3
Q

Staphylococci Species

- Coagulase Positive?

A
  • Staphylococcus aureus
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4
Q

Staphylococci Species

- Coagulase Negative

A
  • Staphylococcus epidermis

- Staphylococcus saprophyticus

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5
Q

Staphylococcus aureus

  • ___ pathogen
  • can cause?
  • some strain ___ to many antibiotics
A
  • Opportunistic
  • septicemia
  • resistant
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6
Q

Staphylococcus epidermidis

  • ____ colonizer
  • produce ___
  • where affects?
A
  • Skin
  • capsule
  • implanted devices (catheters)
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7
Q

Staphylococcus saprophyticus

  • colonizer of ___
  • pathogenesis linked to _____
A
  • inguinal region

- adhesions

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8
Q

S.aureus - Colonization

  • where?
  • how transmitted?
  • surface proteins ___ host proteins using ___
A
  • skin, mucous membranes
  • person-person + fomites
  • bind, adhesions
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9
Q

S.aureus - Characteristics

  • intra/extracellular?
  • pus producing infection
  • forms ____
A
  • intracellular
  • pyogenic
  • forms abscesses
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10
Q

S.aureus - Local Infections (3)

A
  • Skin Abscesses
  • Deep Abscesses
  • Impetigo
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11
Q

Furuncle

A

boil

infection of hair folicle

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12
Q

infection of hair folicle

A

furuncle

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13
Q

Carbuncles

A

infection of several hair follicles

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14
Q

Impetigo

  • what is it?
  • 2 forms?
A
  • superficial skin infection
  • non-bullous = pimple with pus
  • bullous - fluid filled blisters
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15
Q

Ecthyma

A

pus-filled sore

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16
Q

S.aureus - Systemic infections (3)

A
  • septicemia
  • pneumonia
  • endocarditis
17
Q

Osteomyelitis

  • infection of ___
  • from ___ or ____
A
  • bone/bone marrow

- hematogenous spread or fractures

18
Q

S.aureus - Toxin Mediated

  • infection ___
  • effects ___
  • release of ___
A
  • localized
  • systematic
  • toxic proteins
19
Q

Toxic Shock Syndrome

  • symptoms (4)
  • 2 forms?
A
  • acute fever, low BP, rash, desquamation

- menstrual vs nonmenstrual

20
Q

Toxic Shock Syndrome

  • secreted toxins release ____
  • ___ T-cell activation
  • leads to?
A
  • super antigens
  • more T-cell
  • cytokine storm, vascular leakage, organ failure
21
Q

Bacteria produce proteins that interfere with? (3)

A
  • rolling + activation
  • complement deposition
  • chemotaxis
22
Q

Immune Evasion Mechanisms (2)

A

1) Toxins kill leukocytes

2) Resistance to Antibody Mediated Phagocytosis

23
Q

Toxins kill leukocytes

  • ___ toxins kill ___
  • ___ in membrane leads to ___ of cell
A
  • cytolytic, WBC

- holes, lysis

24
Q

Resistance to Antibody Mediated Phagocytosis

  • which strain?
  • binds __ portion of __
  • antibodies bound _____
  • ___ __ receptor __ recognize
  • NO _____
A
  • Staphylococcal Protein A
  • Fc, IgG
  • phagocyte, Fc-receptor, can’t
  • NO complement pathway
25
Q

Methicillin Resistant S.aureus (2)

- where found?

A

1) hospitals

2) community acquired

26
Q

Why hospitals Methicillin Resistant S.aureus?

A

lots of resistant mechanisms

27
Q

Why community acquired Methicillin Resistant S.aureus?

A
  • lack of exposure to health care
  • skin infections
  • necrotizing pneumonia
28
Q

Livestock Associated MRSA

- ___ strains ____ in livestock, which has ____ back to ____

A
  • MRSA, evolved, transmit, humans

Bacteriology (8 decks)

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