Staph Flashcards
Staph Aureus characterisitcs
gram + cocci in clusters aerobic Catalase positive coagulase positive clumping factor + capsule +
what is staph Aureus virulence factor
protein A- binds Fc-igG inhibiting complement activation and phagocytosis
teichoic acid to adhere to epithelial cells
Beta hemolytic
Panton Valentine Leucocidin- wbc cell lysis
Enterotoxin- v/d-> food contamination
TSST-1
MRSA
altered penicillin inding protein from mec A gene
S. Aureus diseases
absesses Boils mild cellulitis lymphadenitis OSteomyelitis Arthritis peri/endocarditis impetigo
chronic granulmatous disease
X linked recessive
neutrophil defect
impaired H2O2
Jobs syndrome
cold abcess
poor neutrophil chemotxis
increased IGE
Scalded skin syndrome
staph exfoliative toxin
do u need to drain a focal staph infection?
yes, abx contain but u still need to drain
Coag neg staph
S. epidermidis-plastic, metal, biofilms
S. Saprophyticus- UTI
S. epidermiditis novobiocin sensitive or no?
sensitive
S. Saprophyticus
novobiocin resistant
-2nd most common cause of uncomplicated UTI in young women
what food is staph enterotoxin associated with
mayo, egg, potato salad
